Patient leaflets and SmPCs, drug interaction checker, official and paediatric dosages, pregnancy and breastfeeding guidance, and NHS pharmacy opening hours — all in one place.
Patient leaflets and SmPCs, drug interaction checker, official and paediatric dosages, pregnancy and breastfeeding guidance, and NHS pharmacy opening hours — all in one place.
Cetirizine dihydrochloride is the active ingredient of Tillomed Allergy and Hayfever Relief 10mg Tablets. Tillomed Allergy and Hayfever Relief 10mg Tablets is an antiallergic medication.
In adults and children aged 6 years and above, Tillomed Allergy and Hayfever Relief 10mg are indicated
• for the relief of nasal and ocular symptoms of seasonal and perennial allergic rhinitis (hayfever, dust allergies, pet allergies).
• for the relief of symptoms of urticaria (skin allergies).
Do not take Tillomed Allergy and Hayfever Relief 10mg Tablets • if you have a severe kidney disease (severe renal failure with creatinine clearance below 10 ml/min);
• if you are allergic to cetirizine dihydrochloride, to any of the other ingredients (listed in section 6), to hydroxyzine or to piperazine derivatives (closely related active ingredients of other medicines).
Warning and precautions Talk to your doctor or pharmacist before taking Tillomed Allergy and Hayfever Relief 10mg Tablets.
If you are a patient with renal insufficiency, please ask your doctor for advice; if necessary, you will take a lower dose. The new dose will be determined by your doctor.
If you have problems passing urine (like spinal cord problems or prostate or bladder problems), please ask your doctor for advice.
If you are an epileptic patient or a patient at risk of convulsions, you should ask your doctor for advice.
No clinically significant interactions have been observed between alcohol (at the blood level of 0.5 per (g/L) corresponding to one glass of wine) and cetirizine used at the recommended doses. However, there are no data available on the safety when higher doses of cetirizine and alcohol are taken together. Therefore, as it is the case with all antihistamines, it is recommended to avoid taking Tillomed Allergy and Hayfever Relief 10mg Tablets with alcohol.
If you are scheduled for allergy testing, ask your doctor if you should stop taking Tillomed Allergy and Hayfever Relief 10mg Tablets for several days before testing. This medicine may affect your allergy test results.
Children Do not give this medicine to children below the age of 6 years because the tablet formulation does not allow the necessary dose adjustments.
Other medicines and Tillomed Allergy and Hayfever Relief 10mg Tablets Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Tillomed Allergy and Hayfever Relief 10mg Tablets with food and drink Food does not affect absorption of Tillomed Allergy and Hayfever Relief 10mg Tablets.
Pregnancy and breast-feeding If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
Tillomed Allergy and Hayfever Relief 10mg Tablets should be avoided in pregnant women.
Accidental use of the drug by a pregnant woman should not produce any harmful effects on the foetus. Nevertheless, the medicine should only be administered if necessary and after medical advice.
Cetirizine passes into breast milk. A risk of side effects in breastfed infants cannot be excluded. Therefore, you should not take Tillomed Allergy and Hayfever Relief 10mg Tablets during breast-feeding unless you have contacted a doctor.
Driving and using machines Clinical studies have produced no evidence of impaired attention, alertness and driving capabilities after taking Tillomed Allergy and Hayfever Relief 10mg Tablets at the recommended dose.
You should closely observe your response to the drug after you have taken Tillomed Allergy and Hayfever Relief 10mg Tablets if you are intending to drive, engage in potentially hazardous activities or operate machinery. You should not exceed the recommended dose.
Tillomed Allergy and Hayfever Relief 10mg Tablets film-coated tablets contains lactose; If you have been told by your doctor that you have an intolerance to some sugars, please contact your doctor before taking this medicinal product.
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
The tablets need to be swallowed with a glass of liquid.
The tablet can be divided into 2 equal doses.
Adults and adolescents above 12 years old: The recommended dose is 10 mg once daily as 1 tablet.
Use in children between 6 and 12 years old: The recommended dose is 5 mg twice daily as a half tablet twice daily.
Patients with renal impairment Patients with moderate renal impairment are recommended to take 5 mg once daily.
If you suffer from severe kidney disease, please contact your doctor or pharmacist who may adjust the dose accordingly.
If your child suffers from kidney disease, please contact your doctor or pharmacist who may adjust the dose according to your child’s needs.
If you feel that the effect of Tillomed Allergy and Hayfever Relief 10mg Tablets is too weak or too strong, please consult your doctor.
Duration of treatment The duration of treatment depends on the type, duration and course of your complaints. Please ask your doctor or pharmacist for advice.
If you take more Tillomed Allergy and Hayfever Relief 10mg Tablets than you should If you think you have taken an overdose of Tillomed Allergy and Hayfever Relief 10mg Tablets please inform your doctor. Your doctor will then decide what measures, if any, should be taken.
After an overdose, the side effects described below may occur with increased intensity. Adverse effects such as confusion, diarrhoea, dizziness, tiredness, headache, ailing, dilating of pupils, itching, restlessness, sedation, somnolence, stupor, abnormal rapid heart rate, tremors and urinary retention have been reported.
If you forget to take Tillomed Allergy and Hayfever Relief 10mg Tablets Do not take a double dose to make up for a forgotten dose.
If you stop taking Tillomed Allergy and Hayfever Relief 10mg Tablets Rarely, pruritus (intense itching) and/or urticaria may return if you stop taking Tillomed Allergy and Hayfever Relief 10mg Tablets.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects are rare or very rare, but you must stop taking the medicine and speak to your doctor straight away if you notice them: • Allergic reactions, including severe reactions and angioedema (serious allergic reaction which causes swelling of the face or throat).
These reactions may start soon after you first take the medicine, or it might start later.
Common side effects (may affect up to 1 in 10 patients)
• Somnolence (sleepiness)
• Dizziness, headache
• Pharyngitis, rhinitis (in children)
• Diarrhea, nausea, dry mouth
• Fatigue
Uncommon side effects (may affect up to 1 in 100 patients)
• Agitation
• Paresthesia (abnormal feelings of the skin)
• Abdominal pain
• Pruritus (itchy skin), rash
• Asthenia (extreme fatigue), malaise
Rare side effects (may affect up to 1 in 1,000 patients)
• Allergic reactions, some severe (very rare)
• Depression, hallucination, aggression, confusion, insomnia
• Convulsions
• Tachycardia (heart beating too fast)
• Liver function abnormal
• Urticaria (hives)
• Oedema (swelling)
• Weight increased
Very rare side effects (may affect up to 1 in 10,000 patients)
• Thrombocytopenia (low levels of blood platelets)
• Tics (habit spasm)
• Syncope, dyskinesia (involuntary movements), dystonia (abnormal prolonged muscular contractions), tremor, dysgeusia (altered taste)
• Blurred vision, accommodation disorder (difficulty focusing), oculogyration (eyes having uncontrolled circular movements)
• Angioedema (serious allergic reaction which causes swelling of the face or throat), fixed drug eruption
• Abnormal elimination of urine (bed wetting, pain and/or difficulty passing water)
Not known frequency of side effects (frequency cannot be estimated from the available data)
• Increased appetite
• Suicidal ideation (recurring thoughts of or preoccupation with suicide), nightmare
• Amnesia, memory impairment
• Vertigo (sensation of rotation or movement)
• Urinary retention (inability to completely empty the urinary bladder)
• Pruritus (intense itching) and/or urticaria upon discontinuation
• Joint pain
• Rash with blisters containing pus
• Hepatitis (inflammation of the liver)
Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects, you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the box and blister. The expiry date refers to the last day of that month.
This medicine does not require any special storage conditions.
What Tillomed Allergy and Hayfever Relief 10mg Tablets contains • The active substance is cetirizine dihydrochloride. Each film-coated tablet contains 10 mg cetirizine dihydrochloride.
• The other ingredients are microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, lactose, magnesium stearate, hypromellose (E 464), titanium dioxide (E171), polydextrose (E1200) and macrogol (E1521).
What Tillomed Allergy and Hayfever Relief 10mg Tablets looks like and contents of the pack White to off-white, film-coated, capsule-shaped tablet, with score on one face of the tablet.
Pack containing 7, 14, or 30 tablets.
Not all pack sizes may be marketed
Marketing Authorisation Holder Tillomed Laboratories Limited
220 Butterfield
Great Marlings
Luton
LU2 8DL
United Kingdom
Manufacturer Tillomed Laboratories Limited
220 Butterfield
Great Marlings
Luton
LU2 8DL
United Kingdom
Tillomed Malta Limited
Malta Life Sciences Park
LS2.01.06. Industrial Estate
San Gwann
SGN 3000
Malta
Other formats
To request a copy of this leaflet in braille, large print or audio, please call 0800 970 6115.
This leaflet was last revised in 12/2025.
Tillomed Laboratories Ltd
Address
220 Butterfield, Great Marlings, Luton, LU2 8DL, UK
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+44 (0)1480 402 400
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[email protected]
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Tillomed Allergy and Hayfever Relief 10 mg Film-Coated Tablets comes as tablet containing 10 mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
The active substance in Tillomed Allergy and Hayfever Relief 10 mg Film-Coated Tablets is cetirizine.
This leaflet reproduces the patient information leaflet approved for Tillomed Allergy and Hayfever Relief 10 mg Film-Coated Tablets, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
Tillomed Allergy and Hayfever Relief 10mg Tablets are indicated in adults and paediatric patients 6 years and above:
- for the relief of nasal and ocular symptoms of seasonal and perennial allergic rhinitis (hayfever, dust allergies, pet allergies).
- for the relief of symptoms of urticaria (skin allergies).
Posology
10 mg once daily (1 tablet).
Special population
Elderly
Data do not suggest that the dose needs to be reduced in elderly subjects provided that the renal function is normal.
Renal impairment
There are no data to document the efficacy/safety ratio in patients with renal impairment. Since cetirizine is mainly excreted via renal route (see section 5.2), in cases no alternative treatment can be used, the dosing intervals must be individualized according to renal function. Refer to the following table and adjust the dose as indicated. To use this dosing table, an estimate of the patient's creatinine clearance (CLcr) in ml/min is needed. The CLcr (ml/min) may be estimated from serum creatinine (mg/dl) determination using the following formula:
Dosing adjustments for adult patients with impaired renal function
| Group | Creatinine clearance (ml/min) | Dosage and frequency |
| Normal Mild Moderate Severe End-stage renal disease - Patients undergoing dialysis | ≥80 50 – 79 30 – 49 <30 <10 | 10 mg once daily 10 mg once daily 5 mg once daily 5 mg once every 2 days Contraindicated |
Hepatic impairment
No dose adjustment is needed in patients with solely hepatic impairment. In patients with hepatic impairment and renal impairment, adjustment of the dose is recommended (see Renal impairment above).
Paediatric population
The tablet formulation should not be used in children under 6 years of age as it does not allow the necessary dose adjustments.
Children aged 6 to 12 years: 5 mg twice daily (a half tablet twice daily).
Adolescents above 12 years: 10 mg once daily (1 tablet).
In paediatric patients suffering from renal impairment, the dose will have to be adjusted on an individual basis taking into account the renal clearance, age and body weight of the patient.
Method of administration
The tablets need to be swallowed with a glass of liquid.
Hypersensitivity to the active substance, to any of the excipients listed in section 6.1, to hydroxyzine or to any piperazine derivatives.
Patients with severe renal impairment with a creatinine clearance below 10 ml/min.
Due to the pharmacokinetic, pharmacodynamic and tolerance profile of cetirizine, no interactions are expected with this antihistamine. Actually, neither pharmacodynamic nor significant pharmacokinetic interaction was reported in drug-drug interactions studies performed, notably with pseudoephedrine or theophylline (400 mg/day).
The extent of absorption of cetirizine is not reduced with food, although the rate of absorption is decreased.
The concurrent use of alcohol or other CNS depressants may cause additional reductions in alertness and impairment of performance, although cetirizine does not potentiate the effect of alcohol (0.5 g/L blood levels).
Pregnancy
For cetirizine prospectively collected data on pregnancy outcomes do not suggest potential for maternal or foetal/embryonic toxicity above background rates.
Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/fetal development, parturition or postnatal development. Caution should nevertheless be exercised when prescribing to pregnant women.
Breast-feeding
Cetirizine passes into breast milk. A risk of side effects in breastfed infants cannot be excluded. Cetirizine is excreted in human milk at concentrations representing 25% to 90% of those measured in plasma, depending on sampling time after administration. Therefore, caution should be exercised when prescribing cetirizine to lactating women.
Fertility
Limited data is available on human fertility, but no safety concern has been identified.
Animal data show no safety concern for human reproduction.
Objective measurements of driving ability, sleep latency and assembly line performance have not demonstrated any clinically relevant effects at the recommended dose of 10 mg. However, patients who experience somnolence should refrain from driving, engaging in potentially hazardous activities or operating machinery. They should not exceed the recommended dose and should take their response to the medicinal product into account.
Symptoms
Symptoms observed after an overdose of cetirizine are mainly associated with CNS effects or with effects that could suggest an anticholinergic effect.
Adverse events reported after an intake of at least 5 times the recommended daily dose are: confusion, diarrhoea, dizziness, fatigue, headache, malaise, mydriasis, pruritus, restlessness, sedation, somnolence, stupor, tachycardia, tremor, and urinary retention.
Management
There is no known specific antidote to cetirizine.
Should overdose occur, symptomatic or supportive treatment is recommended. Gastric lavage may be considered shortly after ingestion of the drug.
Cetirizine is not effectively removed by haemodialysis.
Ask anything about Tillomed Allergy and Hayfever Relief 10 mg Film-Coated Tablets. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.
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