Guidance A-Z — L
118 guidance documents beginning with L.
Lanadelumab for preventing recurrent attacks of hereditary angioedema
Laparoscopic augmentation cystoplasty (including clam cystoplasty)
Laparoscopic cerclage for cervical incompetence to prevent late miscarriage or preterm birth
Laparoscopic cryotherapy for renal cancer
Laparoscopic cystectomy
Laparoscopic deroofing of simple renal cysts
Laparoscopic distal pancreatectomy
Laparoscopic gastrectomy for cancer
Laparoscopic gastric plication for the treatment of severe obesity
Laparoscopic helium plasma coagulation for the treatment of endometriosis
Laparoscopic hysterectomy (including laparoscopic total hysterectomy and laparoscopically assisted vaginal hysterectomy) for endometrial cancer
Laparoscopic insertion of a magnetic ring for gastro-oesophageal reflux disease
Laparoscopic insertion of an inactive implant for gastro-oesophageal reflux disease
Laparoscopic insertion of peritoneal dialysis catheter
Laparoscopic liver resection
Laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina
Laparoscopic mobilisation of the greater omentum for breast reconstruction
Laparoscopic nephrectomy (including nephroureterectomy)
Laparoscopic nephrolithotomy and pyelolithotomy
Laparoscopic partial nephrectomy
Laparoscopic prostatectomy for benign prostatic obstruction
Laparoscopic radical prostatectomy
Laparoscopic removal of uterine fibroids with power morcellation
Laparoscopic renal denervation for loin pain haematuria syndrome
Laparoscopic repair of abdominal aortic aneurysm
Laparoscopic retroperitoneal lymph node dissection for testicular cancer
Laparoscopic surgery for colorectal cancer
Laparoscopic techniques for hysterectomy
Laparoscopic uterine nerve ablation (LUNA) for chronic pelvic pain
Laparoscopic ventral mesh rectopexy for internal rectal prolapse
Lapatinib or trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer that overexpresses HER2
Larotrectinib for treating NTRK fusion-positive solid tumours
LARS for reconstructing damaged intra-articular cruciate knee ligaments
Laser correction of refractive error following non-refractive ophthalmic surgery
Laser lithotripsy for difficult-to-treat bile duct stones
Laser-assisted cerebral vascular anastomosis without temporary arterial occlusion
Latanoprost–netarsudil for previously treated primary open-angle glaucoma or ocular hypertension
Lateral elbow resurfacing for arthritis
Lateral interbody fusion in the lumbar spine for low back pain
LATITUDE NXT Patient Management System for monitoring cardiac devices at home
Lead-I ECG devices for detecting symptomatic atrial fibrillation using single time point testing in primary care
Leadless cardiac pacemaker implantation for bradyarrhythmias
Learning disabilities and behaviour that challenges: service design and delivery
Learning disability: behaviour that challenges
Learning disability: care and support of people growing older
Learning disability: identifying and managing mental health problems
Lebrikizumab for treating moderate to severe atopic dermatitis in people 12 years and over
Ledipasvir–sofosbuvir for treating chronic hepatitis C
Leg ulcer infection: antimicrobial prescribing
Lenalidomide for relapsed or refractory mantle cell lymphoma (terminated appraisal)
Lenalidomide for the treatment of multiple myeloma in people who have received at least 2 prior therapies
Lenalidomide for treating myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality
Lenalidomide maintenance treatment after an autologous stem cell transplant for newly diagnosed multiple myeloma
Lenalidomide plus dexamethasone for multiple myeloma after 1 treatment with bortezomib
Lenalidomide plus dexamethasone for previously untreated multiple myeloma
Lenalidomide with bortezomib and dexamethasone for untreated multiple myeloma (terminated appraisal)
Lenalidomide with rituximab for previously treated follicular lymphoma
Leniolisib for treating activated phosphoinositide 3-kinase delta syndrome in people 12 years and over
Lenvatinib and sorafenib for treating differentiated thyroid cancer after radioactive iodine
Lenvatinib for untreated advanced hepatocellular carcinoma
Lenvatinib with everolimus for previously treated advanced renal cell carcinoma
Lenvatinib with pembrolizumab for untreated advanced renal cell carcinoma
Letermovir for preventing cytomegalovirus disease after a stem cell transplant
Letermovir for preventing cytomegalovirus infection after a kidney transplant (terminated appraisal)
Leukapheresis for inflammatory bowel disease
Leukomed Sorbact for preventing surgical site infection
Lifelight First for monitoring vital signs
LiMAx system for assessing the functional capacity of the liver
Limited macular translocation for wet age-related macular degeneration
Linzagolix for treating moderate to severe symptoms of uterine fibroids
Linzagolix for treating symptoms of endometriosis
LipiFlow thermal pulsation treatment for dry eyes caused by blocked meibomian glands
Liposomal cytarabine–daunorubicin for untreated acute myeloid leukaemia
Liposuction for chronic lipoedema
Liposuction for chronic lymphoedema
Liraglutide for managing obesity in people aged 12 to 17 years (terminated appraisal)
Liraglutide for managing overweight and obesity
Lisocabtagene maraleucel for treating relapsed or refractory aggressive B-cell non-Hodgkin lymphoma after 1 systemic treatment when a stem cell transplant is unsuitable (terminated appraisal)
Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after 2 or more lines of systemic treatment
Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy when a stem cell transplant is suitable
Liver disease
LIVERFASt for assessing and monitoring liver fibrosis, activity and steatosis
Living-donor liver transplantation
Living-donor lung transplantation for end-stage lung disease
Loncastuximab tesirine for treating relapsed or refractory diffuse large B-cell lymphoma and high-grade B-cell lymphoma after 2 or more systemic treatments
Long-acting reversible contraception
Looked-after children and young people
Looked-after children and young people
Lorlatinib for ALK-positive advanced non-small-cell lung cancer that has not been treated with an ALK inhibitor
Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer
Low back pain and sciatica in over 16s
Low back pain and sciatica in over 16s: assessment and management
Low dose rate brachytherapy for localised prostate cancer
Low-energy contact X-ray brachytherapy for rectal cancer
Low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures
Low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk of non-healing
Low-intensity pulsed ultrasound to promote healing of fresh fractures at low risk of non-healing
Low-level laser therapy for preventing or treating oral mucositis caused by radiotherapy or chemotherapy
Lower limb deep vein valve reconstruction for chronic deep venous incompetence
Lower urinary tract symptoms in men
Laparoscopic augmentation cystoplasty (including clam cystoplasty)
Laparoscopic cerclage for cervical incompetence to prevent late miscarriage or preterm birth
Laparoscopic cryotherapy for renal cancer
Laparoscopic cystectomy
Laparoscopic deroofing of simple renal cysts
Laparoscopic distal pancreatectomy
Laparoscopic gastrectomy for cancer
Laparoscopic gastric plication for the treatment of severe obesity
Laparoscopic helium plasma coagulation for the treatment of endometriosis
Laparoscopic hysterectomy (including laparoscopic total hysterectomy and laparoscopically assisted vaginal hysterectomy) for endometrial cancer
Laparoscopic insertion of a magnetic ring for gastro-oesophageal reflux disease
Laparoscopic insertion of an inactive implant for gastro-oesophageal reflux disease
Laparoscopic insertion of peritoneal dialysis catheter
Laparoscopic liver resection
Laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina
Laparoscopic mobilisation of the greater omentum for breast reconstruction
Laparoscopic nephrectomy (including nephroureterectomy)
Laparoscopic nephrolithotomy and pyelolithotomy
Laparoscopic partial nephrectomy
Laparoscopic prostatectomy for benign prostatic obstruction
Laparoscopic radical prostatectomy
Laparoscopic removal of uterine fibroids with power morcellation
Laparoscopic renal denervation for loin pain haematuria syndrome
Laparoscopic repair of abdominal aortic aneurysm
Laparoscopic retroperitoneal lymph node dissection for testicular cancer
Laparoscopic surgery for colorectal cancer
Laparoscopic techniques for hysterectomy
Laparoscopic uterine nerve ablation (LUNA) for chronic pelvic pain
Laparoscopic ventral mesh rectopexy for internal rectal prolapse
Lapatinib or trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer that overexpresses HER2
Larotrectinib for treating NTRK fusion-positive solid tumours
LARS for reconstructing damaged intra-articular cruciate knee ligaments
Laser correction of refractive error following non-refractive ophthalmic surgery
Laser lithotripsy for difficult-to-treat bile duct stones
Laser-assisted cerebral vascular anastomosis without temporary arterial occlusion
Latanoprost–netarsudil for previously treated primary open-angle glaucoma or ocular hypertension
Lateral elbow resurfacing for arthritis
Lateral interbody fusion in the lumbar spine for low back pain
LATITUDE NXT Patient Management System for monitoring cardiac devices at home
Lead-I ECG devices for detecting symptomatic atrial fibrillation using single time point testing in primary care
Leadless cardiac pacemaker implantation for bradyarrhythmias
Learning disabilities and behaviour that challenges: service design and delivery
Learning disability: behaviour that challenges
Learning disability: care and support of people growing older
Learning disability: identifying and managing mental health problems
Lebrikizumab for treating moderate to severe atopic dermatitis in people 12 years and over
Ledipasvir–sofosbuvir for treating chronic hepatitis C
Leg ulcer infection: antimicrobial prescribing
Lenalidomide for relapsed or refractory mantle cell lymphoma (terminated appraisal)
Lenalidomide for the treatment of multiple myeloma in people who have received at least 2 prior therapies
Lenalidomide for treating myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality
Lenalidomide maintenance treatment after an autologous stem cell transplant for newly diagnosed multiple myeloma
Lenalidomide plus dexamethasone for multiple myeloma after 1 treatment with bortezomib
Lenalidomide plus dexamethasone for previously untreated multiple myeloma
Lenalidomide with bortezomib and dexamethasone for untreated multiple myeloma (terminated appraisal)
Lenalidomide with rituximab for previously treated follicular lymphoma
Leniolisib for treating activated phosphoinositide 3-kinase delta syndrome in people 12 years and over
Lenvatinib and sorafenib for treating differentiated thyroid cancer after radioactive iodine
Lenvatinib for untreated advanced hepatocellular carcinoma
Lenvatinib with everolimus for previously treated advanced renal cell carcinoma
Lenvatinib with pembrolizumab for untreated advanced renal cell carcinoma
Letermovir for preventing cytomegalovirus disease after a stem cell transplant
Letermovir for preventing cytomegalovirus infection after a kidney transplant (terminated appraisal)
Leukapheresis for inflammatory bowel disease
Leukomed Sorbact for preventing surgical site infection
Lifelight First for monitoring vital signs
LiMAx system for assessing the functional capacity of the liver
Limited macular translocation for wet age-related macular degeneration
Linzagolix for treating moderate to severe symptoms of uterine fibroids
Linzagolix for treating symptoms of endometriosis
LipiFlow thermal pulsation treatment for dry eyes caused by blocked meibomian glands
Liposomal cytarabine–daunorubicin for untreated acute myeloid leukaemia
Liposuction for chronic lipoedema
Liposuction for chronic lymphoedema
Liraglutide for managing obesity in people aged 12 to 17 years (terminated appraisal)
Liraglutide for managing overweight and obesity
Lisocabtagene maraleucel for treating relapsed or refractory aggressive B-cell non-Hodgkin lymphoma after 1 systemic treatment when a stem cell transplant is unsuitable (terminated appraisal)
Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after 2 or more lines of systemic treatment
Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy when a stem cell transplant is suitable
Liver disease
LIVERFASt for assessing and monitoring liver fibrosis, activity and steatosis
Living-donor liver transplantation
Living-donor lung transplantation for end-stage lung disease
Loncastuximab tesirine for treating relapsed or refractory diffuse large B-cell lymphoma and high-grade B-cell lymphoma after 2 or more systemic treatments
Long-acting reversible contraception
Looked-after children and young people
Looked-after children and young people
Lorlatinib for ALK-positive advanced non-small-cell lung cancer that has not been treated with an ALK inhibitor
Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer
Low back pain and sciatica in over 16s
Low back pain and sciatica in over 16s: assessment and management
Low dose rate brachytherapy for localised prostate cancer
Low-energy contact X-ray brachytherapy for rectal cancer
Low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures
Low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk of non-healing
Low-intensity pulsed ultrasound to promote healing of fresh fractures at low risk of non-healing
Low-level laser therapy for preventing or treating oral mucositis caused by radiotherapy or chemotherapy
Lower limb deep vein valve reconstruction for chronic deep venous incompetence
Lower urinary tract symptoms in men
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