Guidance A-Z — A
226 guidance documents beginning with A.
Ab externo canaloplasty for primary open-angle glaucoma
Ab interno canaloplasty for open-angle glaucoma
Abaloparatide for treating osteoporosis after menopause
Abatacept for treating psoriatic arthritis after DMARDs (terminated appraisal)
Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Abdominal aortic aneurysm: diagnosis and management
Abemaciclib with an aromatase inhibitor for previously untreated, hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer
Abemaciclib with endocrine therapy for adjuvant treatment of hormone receptor-positive, HER2-negative, node-positive early breast cancer at high risk of recurrence
Abemaciclib with fulvestrant for treating hormone receptor-positive, HER2-negative advanced breast cancer after endocrine therapy
Abiraterone (originator and generics) for treating newly diagnosed high-risk hormone‑sensitive metastatic prostate cancer
Abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimen
Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
Abortion care
Abortion care
Abrocitinib, tralokinumab or upadacitinib for treating moderate to severe atopic dermatitis
Acalabrutinib for treating chronic lymphocytic leukaemia
Accuro for guiding epidural or spinal anaesthesia
AccuVein AV400 for vein visualisation
Acne vulgaris: management
Acoramidis for treating transthyretin amyloidosis with cardiomyopathy
Acoustic CR Neuromodulation for adults with chronic subjective tonal tinnitus
AcQMap for mapping the heart atria to target ablation treatment for arrhythmias
Actim Pancreatitis for diagnosing acute pancreatitis
Active B12 assay for diagnosing vitamin B12 deficiency
Acumen IQ sensor for predicting hypotension risk
Acute coronary syndromes
Acute coronary syndromes in adults
Acute heart failure
Acute heart failure: diagnosis and management
Acute kidney injury
Acute kidney injury: prevention, detection and management
Acute respiratory infection in over 16s: initial assessment and management including virtual wards (hospital at home)
Acute upper gastrointestinal bleeding in adults
Acute upper gastrointestinal bleeding in over 16s: management
Acutely ill adults in hospital: recognising and responding to deterioration
Adagrasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer (terminated appraisal)
Adalimumab and dexamethasone for treating non-infectious uveitis
Adalimumab for treating moderate to severe hidradenitis suppurativa
Adalimumab for treating moderate to severe plaque psoriasis
Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
Adalimumab, etanercept, infliximab and abatacept for treating moderate rheumatoid arthritis after conventional DMARDs have failed
Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitor
Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis B
AdenoPlus point-of-care test for diagnosing adenoviral conjunctivitis
Adjunctive colposcopy technologies for assessing suspected cervical abnormalities: the DYSIS colposcope with DYSISmap and the ZedScan I
Adrenal insufficiency: identification and management
Advanced breast cancer: diagnosis and treatment
Advocacy services for adults with health and social care needs
ADXBLADDER for detecting bladder cancer
Afamelanotide for treating erythropoietic protoporphyria
Afatinib for treating advanced squamous non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal)
Afatinib for treating epidermal growth factor receptor mutation-positive locally advanced or metastatic non-small-cell lung cancer
Aflibercept for treating choroidal neovascularisation
Aflibercept for treating diabetic macular oedema
Aflibercept for treating visual impairment caused by macular oedema after branch retinal vein occlusion
Aflibercept for treating visual impairment caused by macular oedema secondary to central retinal vein occlusion
Aflibercept in combination with irinotecan and fluorouracil-based therapy for treating metastatic colorectal cancer that has progressed following prior oxaliplatin-based chemotherapy
Aflibercept solution for injection for treating wet age‑related macular degeneration
Age-related macular degeneration
Agomelatine for the treatment of major depressive episodes (terminated appraisal)
AI technologies for detecting diabetic retinopathy
Air pollution: outdoor air quality and health
Air pollution: outdoor air quality and health
Airglove air warming system for venous access
Aixplorer ShearWave Elastography for ultrasound imaging and assessing suspicious breast lesions
Alair bronchial thermoplasty system for adults with severe difficult to control asthma
Alcohol interventions in secondary and further education
Alcohol-mediated perivascular renal sympathetic denervation for resistant hypertension
Alcohol-use disorders: diagnosis and management
Alcohol-use disorders: diagnosis and management of physical complications
Alcohol-use disorders: diagnosis, assessment and management of harmful drinking (high-risk drinking) and alcohol dependence
Alcohol-use disorders: prevention
Alcohol: preventing harmful use in the community
Alectinib for adjuvant treatment of ALK-positive non-small-cell lung cancer
Alectinib for previously treated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer (terminated appraisal)
Alectinib for untreated ALK-positive advanced non-small-cell lung cancer
Alemtuzumab for treating highly active relapsing–remitting multiple sclerosis
Alere Afinion CRP for C-reactive protein testing in primary care
AlignRT for intracranial stereotactic radiosurgery
AlignRT in breast cancer radiotherapy
Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
Alitretinoin for the treatment of severe chronic hand eczema
Allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus
Alpelisib with fulvestrant for treating hormone receptor-positive, HER2-negative, PIK3CA-mutated advanced breast cancer
Alpha-Stim AID for anxiety disorders
Alteplase for treating acute ischaemic stroke
Amantadine, oseltamivir and zanamivir for the treatment of influenza
AMBLor for identifying low-risk non-ulcerated early-stage cutaneous melanomas
Ambu aScope 4 Broncho for routine diagnostic and therapeutic bronchoscopy
Ambu aScope 4 RhinoLaryngo for visualising upper airways during rhinolaryngoscopy
Ambu aScope4 Broncho for use in unexpected difficult airways
Ambulight PDT for the treatment of non-melanoma skin cancer
Amivantamab for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy
Amivantamab with carboplatin and pemetrexed for untreated EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer
Amivantamab with lazertinib for untreated EGFR mutation-positive advanced non-small-cell lung cancer
AmnioSense for unexplained vaginal wetness in pregnancy
Anakinra for treating Still's disease
Anaphylaxis
Anaphylaxis: assessment and referral after emergency treatment
Ab interno canaloplasty for open-angle glaucoma
Abaloparatide for treating osteoporosis after menopause
Abatacept for treating psoriatic arthritis after DMARDs (terminated appraisal)
Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Abdominal aortic aneurysm: diagnosis and management
Abemaciclib with an aromatase inhibitor for previously untreated, hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer
Abemaciclib with endocrine therapy for adjuvant treatment of hormone receptor-positive, HER2-negative, node-positive early breast cancer at high risk of recurrence
Abemaciclib with fulvestrant for treating hormone receptor-positive, HER2-negative advanced breast cancer after endocrine therapy
Abiraterone (originator and generics) for treating newly diagnosed high-risk hormone‑sensitive metastatic prostate cancer
Abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimen
Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
Abortion care
Abortion care
Abrocitinib, tralokinumab or upadacitinib for treating moderate to severe atopic dermatitis
Acalabrutinib for treating chronic lymphocytic leukaemia
Accuro for guiding epidural or spinal anaesthesia
AccuVein AV400 for vein visualisation
Acne vulgaris: management
Acoramidis for treating transthyretin amyloidosis with cardiomyopathy
Acoustic CR Neuromodulation for adults with chronic subjective tonal tinnitus
AcQMap for mapping the heart atria to target ablation treatment for arrhythmias
Actim Pancreatitis for diagnosing acute pancreatitis
Active B12 assay for diagnosing vitamin B12 deficiency
Acumen IQ sensor for predicting hypotension risk
Acute coronary syndromes
Acute coronary syndromes in adults
Acute heart failure
Acute heart failure: diagnosis and management
Acute kidney injury
Acute kidney injury: prevention, detection and management
Acute respiratory infection in over 16s: initial assessment and management including virtual wards (hospital at home)
Acute upper gastrointestinal bleeding in adults
Acute upper gastrointestinal bleeding in over 16s: management
Acutely ill adults in hospital: recognising and responding to deterioration
Adagrasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer (terminated appraisal)
Adalimumab and dexamethasone for treating non-infectious uveitis
Adalimumab for treating moderate to severe hidradenitis suppurativa
Adalimumab for treating moderate to severe plaque psoriasis
Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
Adalimumab, etanercept, infliximab and abatacept for treating moderate rheumatoid arthritis after conventional DMARDs have failed
Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitor
Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis B
AdenoPlus point-of-care test for diagnosing adenoviral conjunctivitis
Adjunctive colposcopy technologies for assessing suspected cervical abnormalities: the DYSIS colposcope with DYSISmap and the ZedScan I
Adrenal insufficiency: identification and management
Advanced breast cancer: diagnosis and treatment
Advocacy services for adults with health and social care needs
ADXBLADDER for detecting bladder cancer
Afamelanotide for treating erythropoietic protoporphyria
Afatinib for treating advanced squamous non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal)
Afatinib for treating epidermal growth factor receptor mutation-positive locally advanced or metastatic non-small-cell lung cancer
Aflibercept for treating choroidal neovascularisation
Aflibercept for treating diabetic macular oedema
Aflibercept for treating visual impairment caused by macular oedema after branch retinal vein occlusion
Aflibercept for treating visual impairment caused by macular oedema secondary to central retinal vein occlusion
Aflibercept in combination with irinotecan and fluorouracil-based therapy for treating metastatic colorectal cancer that has progressed following prior oxaliplatin-based chemotherapy
Aflibercept solution for injection for treating wet age‑related macular degeneration
Age-related macular degeneration
Agomelatine for the treatment of major depressive episodes (terminated appraisal)
AI technologies for detecting diabetic retinopathy
Air pollution: outdoor air quality and health
Air pollution: outdoor air quality and health
Airglove air warming system for venous access
Aixplorer ShearWave Elastography for ultrasound imaging and assessing suspicious breast lesions
Alair bronchial thermoplasty system for adults with severe difficult to control asthma
Alcohol interventions in secondary and further education
Alcohol-mediated perivascular renal sympathetic denervation for resistant hypertension
Alcohol-use disorders: diagnosis and management
Alcohol-use disorders: diagnosis and management of physical complications
Alcohol-use disorders: diagnosis, assessment and management of harmful drinking (high-risk drinking) and alcohol dependence
Alcohol-use disorders: prevention
Alcohol: preventing harmful use in the community
Alectinib for adjuvant treatment of ALK-positive non-small-cell lung cancer
Alectinib for previously treated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer (terminated appraisal)
Alectinib for untreated ALK-positive advanced non-small-cell lung cancer
Alemtuzumab for treating highly active relapsing–remitting multiple sclerosis
Alere Afinion CRP for C-reactive protein testing in primary care
AlignRT for intracranial stereotactic radiosurgery
AlignRT in breast cancer radiotherapy
Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
Alitretinoin for the treatment of severe chronic hand eczema
Allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus
Alpelisib with fulvestrant for treating hormone receptor-positive, HER2-negative, PIK3CA-mutated advanced breast cancer
Alpha-Stim AID for anxiety disorders
Alteplase for treating acute ischaemic stroke
Amantadine, oseltamivir and zanamivir for the treatment of influenza
AMBLor for identifying low-risk non-ulcerated early-stage cutaneous melanomas
Ambu aScope 4 Broncho for routine diagnostic and therapeutic bronchoscopy
Ambu aScope 4 RhinoLaryngo for visualising upper airways during rhinolaryngoscopy
Ambu aScope4 Broncho for use in unexpected difficult airways
Ambulight PDT for the treatment of non-melanoma skin cancer
Amivantamab for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy
Amivantamab with carboplatin and pemetrexed for untreated EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer
Amivantamab with lazertinib for untreated EGFR mutation-positive advanced non-small-cell lung cancer
AmnioSense for unexplained vaginal wetness in pregnancy
Anakinra for treating Still's disease
Anaphylaxis
Anaphylaxis: assessment and referral after emergency treatment