Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Pyridoxine hydrochloride 50 mg Film-coated Tablets
⚠ This medicine appears to have been discontinued
The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.
If you were prescribed this medicine, other products containing Pyridoxine hydrochloride may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.
What it is and what it is used for
for
Pyridoxine hydrochloride 50 mg film-coated tablets are further referred in this leaflet as Pyridoxine tablets. The active ingredient of Pyridoxine tablets is pyridoxine hydrochloride, which is Vitamin B6. Pyridoxine tablets are used to treat low levels of Vitamin B6 in the body and in the treatment of idiopathic sideroblastic anaemia where the red cells in the blood do not form properly. Pyridoxine tablets can also be used to treat damage to the nerves (peripheral neuritis) caused by isoniazid, a medicine used to treat tuberculosis. 2.
What you need to know before you take it
e Pyridoxine tablets
Do not take Pyridoxine tablets: If you are allergic to pyridoxine hydrochloride or any of the other ingredients of this medicine (listed in section 6). Warnings and precautions Talk to your doctor before taking Pyridoxine tablets if:
- the patient is a child. Pyridoxine tablets are not recommended for children. Other medicines and Pyridoxine tablets Taking another medicine while you are taking Pyridoxine tablets can affect how it or the other medicine works. Please inform your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including those you may have bought yourself without a prescription. Please check with your doctor if you are taking any of the following (or any other medicines):
- levodopa, a medicine used in the treatment of Parkinson's disease
- isoniazid, used to treat tuberculosis
- oral contraceptives
- penicillamine, used to treat arthritis and other conditions. If you have any doubts about whether you should take this medicine, then discuss them with your doctor before taking Pyridoxine tablets. Pregnancy and breast-feeding If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Driving and using machines Pyridoxine tablets do not affect the ability to drive or operate machinery. 3.
How to take it
Pyridoxine tablets
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. Unless you are instructed differently, take your tablets with a glass of water. For the treatment of low levels of Vitamin B6 in the body The usual dose in adults is 50 mg to 150 mg daily in divided doses. For the treatment of idiopathic sideroblastic anaemia The usual adult dose is 100 mg to 400 mg daily in divided doses. For the treatment of nerve damage (peripheral neuritis) caused by isoniazid The usual adult dose is 50 mg three times a day. Elderly If you are elderly, you will require similar doses to those given above. Children Pyridoxine tablets are not recommended for use in children. If you take more Pyridoxine tablets than you should If you accidentally take too many tablets, contact your doctor or pharmacist. If you forget to take Pyridoxine tablets If you forget to take a dose, take another as soon as you remember. If it is almost time for your next dose, then do not take the missed dose. Do not take a double dose to make up for a forgotten tablet. If you stop taking Pyridoxine tablets You should continue to take Pyridoxine tablets for as long as your doctor tells you to. Do not stop taking the medicine without talking to your doctor first. If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
4.
Possible side effects
Like all medicines this medicine can cause side effects, although not everybody gets them. If you take large doses of Pyridoxine tablets for a long time you may develop problems with your nerves (peripheral neuritis). One of the symptoms of peripheral neuritis can be pins and needles. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine. 5.
How to store it
Pyridoxine tablets
Keep this medicine out of the sight and reach of children. Do not take this medicine after the expiry date which is stated on the blister and carton after 'EXP'. The expiry date refers to the last day of that month. Pyridoxine tablets should not be taken if they show signs of deterioration. This medicinal product does not require any special temperature storage conditions. Store in the original package in order to protect from light. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment. 6.
Contents of the pack and other information
What Pyridoxine tablets contain The active substance is pyridoxine hydrochloride. Each film-coated tablet contains 50 mg pyridoxine hydrochloride. The other ingredients are: Core tablet: microcrystalline cellulose, sodium starch glycolate (Type A), colloidal anhydrous silica, magnesium stearate. Film-coating: hypromellose, macrogol, talc, titanium dioxide. What Pyridoxine tablets look like and contents of the pack Pyridoxine tablet is a white to off white, circular, biconvex, film coated tablet with break line on one side and plain on other side. Pack sizes: 10, 14, 20, 28, 30, 40, 50, 56, 60, 70, 80, 84, 90, 100 and 112 tablets. Not all pack sizes may be marketed.
Marketing Authorisation Holder:
Waymade PLC Sovereign House Miles Gray Road Basildon, Essex, SS14 3FR, United Kingdom Manufacturer: Waymade PLC Sovereign House Miles Gray Road Basildon, Essex, SS14 3FR, United Kingdom This leaflet was last revised in March 2025. PL 06464/ 3129
Pyridoxine hydrochloride 50 mg film-coated tablets
To request a copy of this leaflet in Braille, large print or audio format, contact the licence holder at the above address or telephone: 01268 535200 / e-mail: [email protected]
Frequently asked questions about Pyridoxine hydrochloride 50 mg Film-coated Tablets
How do I take Pyridoxine hydrochloride 50 mg Film-coated Tablets?
Pyridoxine hydrochloride 50 mg Film-coated Tablets comes as tablet containing 50mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
What is the active substance in Pyridoxine hydrochloride 50 mg Film-coated Tablets?
The active substance in Pyridoxine hydrochloride 50 mg Film-coated Tablets is pyridoxine hydrochloride.
Are there equivalent medicines to Pyridoxine hydrochloride 50 mg Film-coated Tablets?
Medicines with the same active substance, strength and form include: Pyridoxine 50mg Tablets. They are interchangeable only if your prescriber or pharmacist says so.
Where does this information come from?
This leaflet reproduces the patient information leaflet approved for Pyridoxine hydrochloride 50 mg Film-coated Tablets, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Can I get Pyridoxine hydrochloride 50 mg Film-coated Tablets without a prescription?
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
About this leaflet
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
- Source: electronic medicines compendium (emc), Datapharm
- Active substance: pyridoxine hydrochloride
- Official document: view the original leaflet on emc →
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
4.1. Therapeutic indications
Pyridoxine Hydrochloride is used for isoniazid-induced peripheral neuritis, idiopathic sideroblastic anaemia and Vitamin B6 deficiency states.
4.2. Posology and method of administration
Posology
For isoniazid-induced peripheral neuritis
Adults:
Treatment - 50mg three times daily
Prophylaxis - Not suitable with this dosage form
Children:
This presentation is not recommended
For idiopathic sideroblastic anaemia
Adults:
100 to 400mg daily in divided doses
Children:
This presentation is not recommended
For deficiency states
Adults:
50 to 150mg daily in divided doses
Children:
This presentation is not recommended
Elderly:
Dosage requirements appear to be similar to those for young adults
4.3. Contraindications
Hypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1.
4.4. Special warnings and precautions for use
If symptoms persist or worsen, seek medical advice. Do not exceed the stated dose.
4.5. Interaction with other medicinal products and other forms of interaction
Many drugs may alter the metabolism or bioavailability of pyridoxine, including isoniazid, penicillamine and oral contraceptives, which may increase the requirements for pyridoxine. Pyridoxine hydrochloride may reduce the effect of levodopa, a drug used in the treatment of Parkinsons Disease unless a dopa decarboxylase inhibitor is also given.
4.6. Fertility, pregnancy and lactation
Pregnancy
Data on exposed pregnancies indicate no adverse effects of pyridoxine in therapeutic doses on pregnancy or the health of the foetus or newborn child, or during lactation.
Animal studies are insufficient with respects to effects on pregnancy, embiyonal/foetal development, parturition or postnatal development.
Caution should be exercised when prescribing to pregnant women.
4.7. Effects on ability to drive and use machines
None known.
4.8. Undesirable effects
Long term administration of large doses of pyridoxine is associated with the development of severe peripheral neuritis.
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
4.9. Overdose
a) Symptoms - None reported
b) Treatment - no treatment necessary.
💬 Ask about this leaflet
Ask anything about Pyridoxine hydrochloride 50 mg Film-coated Tablets. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.