Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Paroven 250 mg Capsules
⚠ This medicine appears to have been discontinued
The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.
If you were prescribed this medicine, other products containing Oxerutins may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.
What it is and what it is used for
FOR Paroven Capsules contain oxerutins as the active ingredient, which belongs to a group of medicines which act on small blood vessels (systemic vasoprotectors). Paroven Capsules stabilise the vascular wall, which lead to a reduction in the permeability of the vessels and subsequently to a diminution of swelling (oedema). Paroven Capsules relieve ankle swelling (oedema) due to chronic venous insufficiency (CVI). In patients with varicose veins and some other diseases of the leg veins, these small vessels have an excessive leakage which cause swelling of the ankles. Paroven Capsules also reduce this swelling and relieve the associated common symptoms such as aching, tired, heavy, swollen, painful and restless legs, pins and needles and night cramps. It is recommended that such patients also wear elastic support (usually compression stockings) in CVI; in these cases, Paroven Capsules have been shown to produce additional benefit.
What you need to know before you take it
E PAROVEN CAPSULES Do not take Paroven Capsules if you are:
- allergic to oxerutins or any of the other ingredients of Paroven Capsules listed in Section 6. Warnings and precautions Do not take Paroven Capsules if you have lower leg swelling caused by heart, liver or kidney disease. Children and adolescents Paroven Capsules are not recommended in children and adolescents under 18 years of age as there is no data available. Taking other medicines Please tell your doctor or pharmacist if you are taking, or have recently taken, any other medicines, including those obtained without a prescription. Taking Paroven Capsules with food and drink The capsules can be taken with a drink or at mealtimes. There are no special requirements. Pregnancy, breast-feeding and fertility Paroven Capsules should not be used during the first three months of pregnancy. Do not use if you are pregnant, breast-feeding, think you might be pregnant or are planning to have a baby unless advised by your doctor. Ask your doctor or pharmacist for advice before taking any medicine. Driving and using machines Paroven Capsules have no influence on the ability to drive and use machines. If you experience tiredness or dizziness after using this product, do not drive or use machinery.
How to take it
PAROVEN CAPSULES Always take Paroven Capsules exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. Follow these instructions carefully.
The usual dose is as follows: Adults over 18 years of age and the elderly
- Take 2 capsules (500 mg) twice a day.
- Swallow the capsules whole; do not crush or chew the capsules.
- Can be taken with or without food.
If no improvement in leg swelling is seen, please consult your doctor. If you take more Paroven Capsules than you should If you accidentally take too many Paroven Capsules, or suspect that a child has taken the capsules, contact your doctor or hospital casualty department immediately. Take the carton and capsules with you if possible. If you forget to take Paroven Capsules If you forget to take the capsules, take them as soon as possible unless it is time for the next dose. Do not take double the dose to make up for a forgotten dose. If you have any further questions on the use of this product, ask your doctor or pharmacist.
Possible side effects
Like all medicines, Paroven can cause side effects, although not everybody gets them. The reactions are usually mild. Stop taking the Capsules and tell your doctor immediately if you notice the following very rare symptoms:
- skin rash, swelling of the face, lips, tongue or throat
- hives
- difficulty breathing or swallowing as these may be the first signs of an allergic reaction which may become severe The side effects listed below have also been reported Rare (may affect up to 1 in 1,000 people):
- skin rashes with itching/scaling
- gastrointestinal disorders, including (wind), diarrhoea, abdominal pain, stomach discomfort, dyspepsia (indigestion). Very rare (may affect up to 1 in 10,000 people):
- allergic reactions (see advice above)
- dizziness, headache, flushing, tiredness, nausea, vomiting, photosensitivity reactions (reaction of the skin to
sunlight), alopecia (hair loss), arthralgia (joint pain). These are usually mild and disappear rapidly on stopping treatment.
Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
How to store it
PAROVEN CAPSULES Keep out of the sight and reach of children. Protect from moisture and store in a dry place in the original pack. Do not use Paroven Capsules after the expiry 'EXP' date which is stated on the blister and the carton. The 'EXP' date refers to the last day of that month. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. FURTHER INFORMATION What Paroven Capsules contain The active ingredient is oxerutins 250 mg The other ingredients are polyethylene glycol, gelatin, titanium dioxide (E171), shellac, yellow iron oxide (E172), black iron oxide (E172). What Paroven Capsules look like and contents of the pack Paroven Capsules are opaque, greyish-yellow in colour. Paroven Capsules are available in blister packs of 120 capsules. Marketing Authorisation Holder STADA, Huddersfield, HD7 5QH, UK. Manufacturer STADA Arzneimittel AG, Stadastrasse 2 – 18, 61118 Bad Vilbel, Germany or Recipharm Uppsala AB, Bjorkgatan 30, Uppsala Domkyrkofors., Uppsala, 753 23, Sweden. For any information about this medicinal product, please contact the Marketing Authorisation Holder. This leaflet was last revised in February 2026
9298202 2602 GB – KR/Drugs/KTK/25/460/2001 PET005702-GB
Frequently asked questions about Paroven 250 mg Capsules
How do I take Paroven 250 mg Capsules?
Paroven 250 mg Capsules comes as capsule containing 250mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
What is the active substance in Paroven 250 mg Capsules?
The active substance in Paroven 250 mg Capsules is oxerutins.
Where does this information come from?
This leaflet reproduces the patient information leaflet approved for Paroven 250 mg Capsules, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Can I get Paroven 250 mg Capsules without a prescription?
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
About this leaflet
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
- Source: electronic medicines compendium (emc), Datapharm
- Active substance: oxerutins
- Official document: view the original leaflet on emc →
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
4.1. Therapeutic indications
Relief of symptoms of oedema associated with chronic venous insufficiency.
4.2. Posology and method of administration
Posology
Adults and elderly: 2 capsules (500mg) twice daily.
Patients with heart, renal or hepatic impairment
Patients who have oedema of the lower limbs due to heart, kidney or liver disease should not use Paroven because the effect of O-(beta- hydroxyethyl)-rutosides has not been shown in these indications.
Paediatric population
The safety and efficacy of Paroven in children and adolescents aged less than 18 years has not yet been established. No data are available.
Method of administration
Oral use.
4.3. Contraindications
Hypersensitivity to O-(beta-hydroxyethyl)-rutosides or to any of the excipients listed in section 6.1.
4.4. Special warnings and precautions for use
Patients with heart, renal or hepatic impairment
Treatment of leg oedema due to cardiac, renal or hepatic disease should be directed to the underlying cause; Paroven should not be used in these conditions. If leg pain and swelling do not improve, or get worse, the patient should consult their doctor.
4.5. Interaction with other medicinal products and other forms of interaction
None reported. Oxerutins have been shown not to interact with warfarin anticoagulants.
4.6. Fertility, pregnancy and lactation
Pregnancy
Data on a limited number of exposed pregnancies indicate no adverse effects of O-(beta-hydroxyethyl)-rutosides on pregnancy or on the health of the fetus/new-born child. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/fetal development, parturition or postnatal development (see section 5.3 Preclinical safety data).
Nevertheless, according to generally accepted safety recommendations, HR should not be used during the first three months of pregnancy.
Breastfeeding
In animal studies, traces of HR were found in the fetuses and in the milk of breast-feeding dams. These minor amounts of HR are of no clinical significance.
Fertility
Animal studies did not indicate effects on fertility following administration of O-(ß-hydroxyethyl)-rutosides.
4.7. Effects on ability to drive and use machines
Paroven has no or negligible influence on the ability to drive and use machines.
In rare instances tiredness and dizziness have been reported in patients using this product. If affected, patients are advised not to drive or operate machines.
4.8. Undesirable effects
Paroven may cause in rare cases gastrointestinal side effects or skin reactions like gastrointestinal disorder, flatulence, diarrhea, abdominal pain, stomach discomfort, dyspepsia, rash, pruritus or urticaria. Very rare is the occurrence of dizziness, headache, flushing, fatigue or hypersensitivity reactions like anaphylactoid reactions.
Adverse reactions are listed below by system organ class and frequency. Frequencies are defined as: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000), or not known (can not to be estimated from available data). Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness.
System Organ Class (SOC)
Frequency
Adverse Reaction
Immune system disorders
Very rare
Anaphylactoid reactions
Hypersensitivity reactions
Nervous system disorders
Very rare
Dizziness
Headache
Vascular disorders
Very rare
Flushing
Gastro-intestinal disorders
Rare
Gastrointestinal disorder,
Flatulence
Diarrhea
Abdominal pain
Stomach discomfort
Dyspepsia
Skin and subcutaneous tissue disorders
Rare
Rash
Pruritus
Urticaria
Very Rare
Photosensitivity
Alopecia
General disorders and administration site conditions
Very rare
Fatigue
Musculoskeletal, connective tissue and bone disorders
Very Rare
Arthralgia
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medical product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme, www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
4.9. Overdose
No cases of overdosage with symptoms have been reported. No specific antidotes are known.
💬 Ask about this leaflet
Ask anything about Paroven 250 mg Capsules. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.