Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Nystaform Cream
⚠ This medicine appears to have been discontinued
The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.
If you were prescribed this medicine, other products containing Nystatin, Chlorhexidine hydrochloride may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.
What it is and what it is used for
FOR Nystaform Cream is a light yellow cream for application to the skin. It is used to treat skin infections caused by either fungi and/or bacteria, such as ringworm, athlete's foot and infected nappy rash.
What you need to know before you take it
E NYSTAFORM CREAM Do not use Nystaform Cream
- If you are allergic to nystatin, chlorhexidine hydrochloride or any of the other ingredients of this medicine (listed in section 6). Warnings and precautions Talk to your doctor or pharmacist before using Nystaform Cream. Nystaform Cream may in rare cases cause severe allergic reactions, leading to a drop in blood pressure and even to unconsciousness. Early symptoms of a severe allergic reaction may be skin rash or asthma. If you notice these symptoms, stop using Nystaform Cream and contact your doctor as soon as possible (see under section 4). Take special care with Nystaform Cream
- Nystaform Cream is for external use only and should not be used near your eyes, mouth or be swallowed.
- If swallowed accidentally, seek medical advice immediately.
- If Nystaform Cream gets in your eyes accidentally, you should rinse your eyes immediately and contact your doctor. If you are usure about anything, please ask your doctor or pharmacist. Other medicines and Nystaform Cream Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Pregnancy, breast-feeding and fertility Do not use Nystaform Cream if you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Important information about some of the ingredients of Nystaform Cream Nystaform Cream contains cetostearyl alcohol Nystaform Cream contains the ingredient cetostearyl alcohol which may cause local skin reactions (e.g. contact dermatitis) in some patients. Nystaform Cream contains benzyl alcohol This medicine contains 10 mg benzyl alcohol in each gram of cream. Benzyl alcohol may cause allergic reactions and mild local irritation. 1/NC/05/2207/742.v3
How to take it
NYSTAFORM CREAM Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. For application to the skin only. Apply the cream to the infected area two or three times daily. The cream should be applied for one week after your infection has healed. If the infected area has not improved within seven days of starting treatment, consult your doctor. If the condition does not improve within 14 days of starting treatment, or if a new infection appears, you should stop using Nystaform Cream and consult your doctor. An alternative treatment may be needed. If you forget to use Nystaform Cream Apply the cream as soon as you remember and then continue the rest of your treatment as usual. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. If you experience any of the following reactions stop using Nystaform Cream and get immediate medical help: Swelling of the face, lips, tongue or throat; a red itchy skin rash; wheezing or difficulty breathing; feeling faint and dizzy; a strange metallic taste in the mouith; collaspe. You may be having an allergic reaction. If you develop a rash or your skin becomes itchy, red, dry or inflamed where you have used this medicine, stop using it and talk to your doctor or pharmacist. Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
How to store it
NYSTAFORM CREAM Keep this medicine out of the sight and reach of children. Do not store above 25oC Do not use this medicine after the expiry date which is stated on the tube and on the carton after EXP. The expiry date refers the the last day of that month. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Contents of the pack and other information
What Nystaform Cream contains
- The active substances are nystatin (100,000 i.u./g), chlorhexidine hydrochloride (1% w/w).
- The other ingredients are benzyl alcohol, cetostearyl alcohol, cetyl esters wax, octyldodecanol, polysorbate 60, sorbitan stearate and purified water. What Nystaform Cream looks like and contents of the pack Nystaform Cream is a light yellow cream which comes in 30g aluminium tubes. Marketing Authorisation Holder and Manufacturer Marketing Authorisation Holder Typharm Ltd, Unit 1, 39 Mahoney Green, Rackheath, Norwich, NR13 6JY. Manufacturer PURNA PHARMACEUTICALS NV/SA, Rijksweg 17, 2870 Puurs, Belgium This leaflet was last revised in August 2022.
1/NC/05/2207/742.v3
Frequently asked questions about Nystaform Cream
How do I take Nystaform Cream?
Nystaform Cream comes as cream. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
What is the active substance in Nystaform Cream?
The active substance in Nystaform Cream is nystatin, chlorhexidine hydrochloride.
Where does this information come from?
This leaflet reproduces the patient information leaflet approved for Nystaform Cream, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Can I get Nystaform Cream without a prescription?
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
About this leaflet
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
- Source: electronic medicines compendium (emc), Datapharm
- Active substance: nystatin, chlorhexidine hydrochloride
- Official document: view the original leaflet on emc →
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
4.1. Therapeutic indications
Nystaform cream is indicated for the treatment of infected skin conditions where fungal (particularly monilial) and/or bacterial infections are present.
4.2. Posology and method of administration
Posology
Adults and Children:
Apply to infected areas 2-3 times daily. Continue application for 1 week after lesions have healed.
The patient should be advised that if the condition has not improved within seven days, to return to the surgery for further consultation. If the condition does not improve within 14 days of starting treatment, then an alternative treatment should be substituted.
Method of adminstration
For topical application only.
4.3. Contraindications
Known hypersensitivity to the active substance, especially in those with a history of possible chlorhexidine-related allergic reactions (see sections 4.4 and 4.8), or to any of the excipients listed in section 6.1.
4.4. Special warnings and precautions for use
For external use only. Avoid contact with eyes. If sensitivity occurs, or if new infection appears, discontinue use and institute alternative therapy.
Cetostearyl alcohol may cause local skin reactions (e.g. contact dermatitis).
This medicine contains 10 mg benzyl alcohol in each gram of cream. Benzyl alcohol may cause allergic reactions and mild local irritation.
Nystaform Cream contains chlorhexidine. Chlorhexidine is known to induce hypersensitivity, including generalised allergic reactions and anaphylactic shock. The prevalence of chlorhexidine hypersensitivity is not known, but available literature suggests this is likely to be very rare. Nystaform Cream should not be administered to anyone with a potential history of an allergic reaction to a chlorhexidine-containing compound (see sections 4.3 and 4.8).
4.5. Interaction with other medicinal products and other forms of interaction
None stated.
4.6. Fertility, pregnancy and lactation
As with all drugs, nystatin should be administered with caution during the early months of pregnancy and its use requires that the anticipated benefits outweigh the possible risks.
4.7. Effects on ability to drive and use machines
None stated.
4.8. Undesirable effects
Skin disorders
Frequency not known: Allergic skin reactions such as dermatitis, pruritus, erythema, eczema, rash, urticaria, skin irritation, and blisters.
Immune disorders
Frequency not known: Hypersensitivity including anaphylactic shock (see sections 4.3 and 4.4).
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
4.9. Overdose
Nystatin is poorly absorbed from the gastro-intestinal tract. In the event of accidental oral ingestion, routine measures such as gastric lavage should be performed as soon as possible after ingestion.
🇷🇴 Known in Romania as
Medicines sold in Romania with the same active substance: Cunoscut în România ca
⚠ Not the same combination. This medicine contains Nystatin, Chlorhexidine hydrochloride. The products below do not contain exactly the same set of active substances — they are not direct substitutes.
⚠ Same active substance, but a different pharmaceutical form (for example a gel instead of a tablet). Not interchangeable — ask a pharmacist.
- NISTATINA ATB 100000 UI prescription partial — not the same combinationNYSTATINUM · rectal / vaginal
- NISTATINA ATB 500000 UI prescription partial — not the same combinationNYSTATINUM · taken by mouth
- CORSODYL MINT MOUTHWASH 2 mg/ml over the counter partial — not the same combinationCHLORHEXIDINUM · taken by mouth
Some of these do not contain exactly the same active substances — check each one. The strength, the form and whether you need a prescription can differ. Always ask a pharmacist before you switch. Romanian medicines in the UK →
🇵🇱 Known in Poland as
Medicines sold in Poland with the same active substance: W Polsce znany jako
⚠ Not the same combination. This medicine contains Nystatin, Chlorhexidine hydrochloride. The products below do not contain exactly the same set of active substances — they are not direct substitutes.
⚠ Same active substance, but a different pharmaceutical form (for example a gel instead of a tablet). Not interchangeable — ask a pharmacist.
- Nystatyna Teva partial — not the same combinationNystatinum · taken by mouth
- Nystatyna VP partial — not the same combinationNystatinum · rectal / vaginal
- Nystapol partial — not the same combinationNystatinum · taken by mouth
- Nyscandin partial — not the same combinationNystatinum · taken by mouth
- Nystatin TZF partial — not the same combinationNystatinum · taken by mouth
Some of these do not contain exactly the same active substances — check each one. The strength, the form and whether you need a prescription can differ. Always ask a pharmacist before you switch. Polish medicines in the UK →
💬 Ask about this leaflet
Ask anything about Nystaform Cream. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.