Pharmacy Guide

Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.

Pharmacy Guide

Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.

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Noriday 350 microgram Tablets

⚠ This medicine appears to have been discontinued

The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.

If you were prescribed this medicine, other products containing Norethisterone may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.

Active substance: Norethisterone
Source: electronic medicines compendium (emc)
Official leaflet: Read the PIL on emc

What it is and what it is used for

for Noriday is a progestogen-only contraceptive pill, or 'POP' for short. Noriday contains the active substance norethisterone. Noriday helps to prevent you becoming pregnant. It does this in several ways

  • It thickens the fluid at the entrance to your womb and this makes it hard for sperm to travel through and enter the womb
  • It also changes the lining of your womb so that a fertilised egg cannot grow there
  • Sometimes it stops your ovaries releasing an egg

What you need to know before you take it

e Noriday Do not take Noriday if you:

  • are allergic to norethisterone or any of the other ingredients of this medicine (listed in section 6)
  • are or think you may be pregnant
  • have had, or think you may have hormone-dependent cancer of the breast, cervix, vagina, or womb
  • have or ever had acute or severe chronic liver disease including: • past or present tumours • jaundice (yellowing of the skin or eyes) and other types of jaundice such as DubinJohnson Syndrome and Rotor Syndrome
  • active liver disease or liver tumours
  • have had the following during pregnancy: • pruritus (itching of the whole body)

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• • • • • •

• jaundice (yellowing of the skin and eyes) for which your doctor could not find a cause have disorders of lipid (fat) metabolism have unexplained vaginal bleeding have never had a period or suffer from lack of periods (amenorrhoea) have inflamed veins (thrombophlebitis) have thrombosis (blood clots) have heart disease, or you have had a stroke

Warnings and precautions Talk to your doctor before taking Noriday if you suffer from or have ever suffered from:

  • epilepsy
  • multiple sclerosis
  • porphyria (a rare inherited blood disease)
  • tetany (muscle twitches)
  • otosclerosis (an inherited form of deafness which sometimes gets worse during pregnancy)
  • diabetes or have a family history of diabetes
  • gallstones
  • impaired carbohydrate tolerance
  • migraine headaches – if you develop migraine headaches you should consult your doctor
  • heart or kidney problems
  • depression
  • liver disease
  • varicose veins
  • high blood pressure
  • asthma Psychiatric disorders Some women using hormonal contraceptives including Noriday have reported depression or depressed mood. Depression can be serious and may sometimes lead to suicidal thoughts. If you experience mood changes and depressive symptoms contact your doctor for further medical advice as soon as possible. Before you take Noriday you should also tell your doctor if you wear contact lenses. If you are obese or have history of pre-eclampsia and are more than 35 years of age, your doctor will discuss the risk/benefit of using oral contraceptives as compared to other methods of contraception due to additional risks. Medical check-ups Your doctor or clinic will give you regular check-ups while you are taking Noriday. Your blood pressure will be checked before you start using the pill and then at regular intervals whilst you are on the pill. If your blood pressure goes up, your doctor may tell you to stop taking Noriday. They may also check your breasts and reproductive organs. All women are encouraged to undergo cervical smear tests at regular intervals. Other medicines and Noriday Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

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The following medicines may stop Noriday from working properly (the condition they treat is shown in brackets): • • • • • • • • • • • • • • • •

the herbal remedy St John's wort – Latin name Hypericum perforatum (depression) carbamazepine (epilepsy) oxacarbazepine (epilepsy) phenytoin (epilepsy) phenobarbital (sleeplessness, anxiety, epilepsy) primidone (epilepsy) topiramate (epilepsy) nelfinavir (HIV-Human Immunodeficiency Virus – infection) nevirapine (HIV infection and AIDS) ritonavir (HIV infection and AIDS) rifabutin (bacterial infection) rifampicin (bacterial infection) griseofulvin (fungal infection) ampicillin (bacterial infection) doxycycline (bacterial infection) modafinil (narcolepsy i.e. daytime sleep)

If you do need to take any of the medicines listed above, Noriday may not be suitable for you. Your doctor will advise you whether to stop taking these medicines or use an additional contraceptive method, such as a condom whilst taking Noriday. Noriday may change the effects of other medicines. Tell your doctor if you are taking prednisone, prednisolone, cloprednol or any other corticosteroids, as Noriday may not be suitable for you. Pregnancy, breast-feeding and fertility Pregnancy If you think you may have become pregnant whilst using Noriday, tell your doctor immediately. If you become pregnant while you are taking this type of pill there is a slightly higher chance that it could be an ectopic pregnancy (a pregnancy developing outside the womb). Do not take Noriday if you are pregnant or trying to become pregnant. If you miss two consecutive periods while you are taking Noriday, tell your doctor or pharmacist. You will need to have a pregnancy test before you continue to take Noriday. Breast-feeding Noriday does not prevent the breast from producing milk. However, it is better for the baby that for the first few weeks after birth its mother's milk contains no trace of any medicines, including Noriday. Sexually transmitted diseases Noriday helps to prevent you from becoming pregnant. It will not protect you against sexually-transmitted diseases, including AIDS. For safer sex, use a condom as well as your usual contraceptive. Driving and using machines No effects on the ability to drive or use machines have been seen with Noriday. Smoking Page 3 of 7

Smoking increases the risk to your health and increases some of the risks of the combined pill. It is not known if these risks also apply to the progestogen-only pill. It is recommended that you give up smoking. Noriday contains lactose monohydrate If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

How to take it

Noriday Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

  • Start on the first day of your next period. This is 'day one' of your cycle, the day when b leeding starts
  • Take one pill each day and swallow the pill with water
  • You can take the pill at any time that suits you, but you must take it at about the same time each day
  • The pack is marked with the days of the week to help you remember to take your pills
  • Follow the direction of the arrows on the pack and take a pill every day until the pack is empty . When you finish the first pack, start a new pack on the next day. This means that you will be taking pills through your period
  • There must be no breaks between packs
  • For the first seven days of the first pack you should also use a condom, or a cap and spermicide
  • If you are three or more hours late taking your pill, follow the instructions under 'What do I do if I forget to take a pill?' What do I do if I forget to take a pill?
  • If you are three or more hours late taking your pill you may not be protected from pregnancy
  • Take the pill as soon as you remember, and take the next one at the normal time
  • This may mean taking two pills in one day
  • Continue to take your pills as normal but also use a condom for the next seven days What do I do if my periods are different? This is quite normal with the progestogen-only pill. Sometimes the time between periods, and the length of the periods is different. There may be bleeding between periods, called 'breakthrough bleeding'. This tends to happen more in the first few months of taking Noriday. If your periods seem different, do not stop taking Noriday but mention it to your doctor or healthcare professional at your next check-up. What do I do if I miss a period? This may happen with this type of pill. If you have taken all your pills properly, you are very unlikely to be pregnant. Take your next pack as normal. If you miss a second period see your doctor or healthcare professional at once. What do I do if I take too many Noriday pills? If you take more than one pill there should be no problems, but you may experience feeling sick or actually being sick, breast enlargement and vaginal bleeding. If you take too many pills or you find out that someone else has taken a lot of pills, contact a doctor immediately. What do I do if I have a stomach upset or I am sick? Noriday may not work if you are sick or have diarrhoea. Continue to take your pills as normal but use a condom while you are ill and for the next seven days. Page 4 of 7

What do I do if I am having an operation? If you are going to have an operation, or if you are ill or injured and there may be a risk of blood clots, please mention to your doctor that you take Noriday. Noriday should be discontinued 4 weeks prior to surgery and can normally be re-started 2 weeks following surgery. Your doctor will discuss what is relevant for you. What do I do if I am changing pill brands? Take the first pill of your new pack on the day after you finish your old pack. Do not leave any break at all. What do I do if I want a baby? Stop taking Noriday if you want to have a baby. It is helpful to wait until your regular periods return before you try to get pregnant. Therefore it is recommended that you stop taking Noriday tablets three months before a planned pregnancy. You can use another type of contraceptive, such as a condom until then. Once you have had a period it will be easier to work out when the baby is due. However, if you get pregnant as soon as you stop taking Noriday, this is not harmful. If you wish to become pregnant, you should contact your doctor or healthcare professional about stopping Noriday. What do I do if I have just had a baby? You can use Noriday after having a baby whether you are breast-feeding or not. You can start taking the pill from day 21 after childbirth. This protects you as soon as you have taken the first pill. If you start later than this you may not be protected until you have taken the pill for another seven days. If you have had a miscarriage or abortion you can start taking the pill straightaway and will be protected immediately. What do I do if I have had a miscarriage or abortion? You can start taking the pill straight away and will be protected immediately. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. If any of the side effects gets serious, or if you notice any side effects not listed in the leaflet please tell your doctor. These effects should become less of a problem as your body gets used to the pills. Reasons to get medical help immediately Stop taking the pills at once and tell your doctor if:

  • You become jaundiced (your skin or the whites of your eyes look yellow) Also seek medical attention immediately if:
  • You have a sudden, severe pain in your chest
  • You suddenly become short of breath
  • You have an unusual, severe or long headache
  • Your sight is affected in any way
  • You find it difficult to speak
  • You collapse or faint
  • Any part of your body suddenly feels weak or numb
  • You have a severe pain in one of your calves

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These could be warning signs of thrombosis (a blood clot). Other side effects that you might have include:

  • stomach upsets
  • changes in your weight
  • swollen or sore breasts
  • headaches
  • changes in sex drive
  • migraines
  • changes in appetite
  • gallstones
  • a rash
  • feeling tired
  • feeling nervous
  • feeling depressed
  • high blood pressure
  • irregular periods
  • a liver disorder, such as a benign liver tumour. These mostly do not cause any symptoms but can sometimes be felt. Benign liver tumours can sometimes cause severe abdominal pain. Possible risk of breast cancer Every woman is at risk of breast cancer whether or not she takes the oral contraceptives (OC). Breast cancer is rare under the age of 40 but the risk increases as a woman gets older. Whilst taking the OC there is a slightly higher incidence of breast cancer when comparing women of the same age. When you stop taking the OC, the risk is reduced such that 10 years after stopping OC, the risk of finding breast cancer is the same as for women who have never taken the OC. Where breast cancer is identified it seems less likely to have spread in women who take OC than in women who do not. It is not certain whether the OC causes the increased risk of breast cancer. It may be that women taking the OC are examined more often, so that breast cancer is noticed earlier. The risk of finding breast cancer is not affected by how long a woman takes a pill like Noriday, POP, but by the age at which she stops. This is because the risk of breast cancer strongly increases as a woman gets older. For 10.000 women who take a POP for 5 years and then stop any increased risk of finding breast cancer in the following 10 years increases with age, as shown below: Age at time of stopping 20 30 40 Number of cases in those who have never taken the 4 44 160 Pill Additional cases in those who have used the Pill 1 2-3 10 The possible small extra risk of being diagnosed with breast cancer has to be weighed against the known benefits of taking the progestogen-only pill.

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Taking any medicine carries some risk. You can use the information in this leaflet, and the advice your doctor or clinic has given you to weigh up the risks of taking the OC. Don't be embarrassed, ask as many questions as you need to. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

How to store it

Noriday Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and on the blister after EXP. The expiry date refers to the last day of that month. Do not store above 25o C. Keep the blister in the outer carton in order to protect from light and moisture. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Contents of the pack and other information

What Noriday contains

  • The active substance is norethisterone. Each pill contains 350 micrograms of norethisterone.
  • The other ingredients in each tablet are maize starch, povidone, magnesium stearate and lactose monohydrate. Please also refer to Section 2, 'Noriday contains lactose monohydrate'. What Noriday looks like and contents of the pack Noriday pills are white, round tablets and have 'SEARLE' debossed on one side and 'NY' on the other side. Noriday tablets are supplied in blister strips in cartons containing 28 or 84 tablets. Not all pack sizes may be marketed. Marketing Authorisation Holder and Manufacturer Marketing Authorisation Holder: Pfizer Limited Ramsgate Road Sandwich Kent CT13 9NJ Manufacturer: Piramal Healthcare UK Limited Morpeth Northumberland NE61 3YA This leaflet was last revised in 01/2023 Ref: NO 9_1 UK

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Frequently asked questions about Noriday 350 microgram Tablets

How do I take Noriday 350 microgram Tablets?

Noriday 350 microgram Tablets comes as tablet containing 350mcg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.

What is the active substance in Noriday 350 microgram Tablets?

The active substance in Noriday 350 microgram Tablets is norethisterone.

Where does this information come from?

This leaflet reproduces the patient information leaflet approved for Noriday 350 microgram Tablets, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.

Can I get Noriday 350 microgram Tablets without a prescription?

Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.

About this leaflet

The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.

Medical disclaimer: This page is for information only and does not replace advice from your doctor or pharmacist. Always read the leaflet supplied with your medicine. If you are unwell, call NHS 111; in an emergency, call 999.

Medicines with the same active substance: Norethisterone (8 medicines)
See every medicine containing this substance, or browse the full A–Z of active substances.
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
Technical information intended for healthcare professionals (doctors and pharmacists). The Summary of Product Characteristics (SmPC) is the official document approved by the MHRA/EMA. It does not replace the patient leaflet or a doctor’s advice.

4.1. Therapeutic indications

Noriday is a progestogen-only oral contraceptive. It is particularly useful for women for whom oestrogens may not be appropriate.

4.2. Posology and method of administration

Posology

Starting on the first day of menstruation, one pill every day without a break in medication for as long as contraception is required. Additional contraceptive precautions (such as a condom) should be taken for the first 7 days of the first pack. Pills should be taken at the same time each day.

Missed pills

If a pill is missed within 3 hours of the correct dosage time then the missed pill should be taken as soon as possible; this will ensure that contraceptive protection is maintained. If a pill is taken 3 or more hours late it is recommended that the woman takes the last missed pill as soon as possible and then continues to take the rest of the pills in the normal manner. However, to provide continued contraceptive protection it is recommended that an alternative method of contraception, such as a condom, is used for the next 7 days.

Changing from another oral contraceptive

In order to ensure that contraception is maintained it is advised that the first pill is taken on the day immediately after the patient has finished the previous pack.

Use after childbirth, miscarriage or abortion

The first pill should be taken on the 21st day after childbirth. This will ensure the patient is protected immediately. If there is any delay in taking the first pill, contraception may not be established until 7 days after the first pill has been taken. In these circumstances women should be advised that extra contraceptive methods will be necessary.

After a miscarriage or abortion patients can take the first pill on the next day; in this way they will be protected immediately.

Vomiting and diarrhoea

Gastrointestinal upsets, such as vomiting and diarrhoea, may interfere with the absorption of the pill leading to a reduction in contraceptive efficacy. Women should continue to take Noriday, but they should also be advised to use another contraceptive method during the period of gastrointestinal upset and for the next 7 days.

Method of administration

For oral use.

4.3. Contraindications

The contraindications for progestogen-only oral contraceptives are:

i. known, suspected, or a past history of breast, genital or hormone dependent cancer

ii. acute or severe chronic liver diseases including past or present liver tumours, Dubin-Johnson or Rotor syndrome

iii. active liver disease

iv. history during pregnancy of idiopathic jaundice or severe pruritus;

v. disorders of lipid metabolism

vi. undiagnosed abnormal vaginal bleeding

vii. known or suspected pregnancy

viii. hypersensitivity to the active substance or to any of the excipients listed in section 6.1.

Combined oestrogen/progestogen preparations have been associated with an increase in the risk of thromboembolic and thrombotic disease. Risk has been reported to be related to both oestrogenic and progestogenic activity. In the absence of long term epidemiological studies with progestogen-only oral contraceptives, it is required that the existence, or history of thrombophlebitis, thromboembolic disorders, cerebral vascular disease, myocardial infarction, angina, or coronary artery disease be described as a contraindication to Noriday as it is to oestrogen containing oral contraceptives.

4.4. Special warnings and precautions for use

Assessment of women prior to starting oral contraceptives (and at regular intervals thereafter) should include a personal and family medical history of each woman. Physical examination should be guided by this and by the contraindications (section 4.3) and warnings (section 4.4) for this product. The frequency and nature of these assessments should be based upon relevant guidelines and should be adapted to the individual woman, but should include measurement of blood pressure and, if judged appropriate by the clinician, breast, abdominal and pelvic examination including cervical cytology.

Malignant hepatic tumours have been reported on rare occasions in long-term users of contraceptives. Benign hepatic tumours have also been associated with oral contraceptive usage. A hepatic tumour should be considered in the differential diagnosis when upper abdominal pain, enlarged liver or signs of intra-abdominal haemorrhage occur.

Hepatic adenoma - In very rare cases, hepatic adenomas may be associated with progesterone-only pill (POP) use. In some cases the hepatic adenoma may decrease in size or become undetectable after discontinuation of norethisterone. Rupture of hepatic adenomas may cause death through intra-abdominal haemorrhage. In extremely rare cases, hepatocellular carcinoma may be associated with combined oral contraceptives use.

A statistical association between the use of oral contraceptives and the occurrence of thrombosis, embolism or haemorrhage has been reported. Patients receiving oral contraceptives should be kept under regular surveillance, in view of the possibility of development of conditions such as thrombo-embolism.

The risk of coronary artery disease in women taking oral contraceptives is increased by the presence of other predisposing factors such as cigarette smoking, hypercholesterolemia, obesity, diabetes, history of pre-eclamptic toxaemia and increasing age. After the age of thirty-five years, the patient and physician should carefully re-assess the risk/benefit ratio of using oral contraceptives as opposed to alternative methods of contraception.

Noriday should be discontinued at least 4 weeks before elective surgery or during periods of prolonged immobilisation. It would be reasonable to resume Noriday 2 weeks after surgery provided the woman is ambulant. However, every woman should be considered individually with regard to the nature of the operation, the extent of immobilisation, the presence of additional risk factors and the chance of unwanted conception.

Noriday should be discontinued if there is a gradual or sudden, partial or complete loss of vision or any evidence of ocular changes, onset or aggravation of migraine or development of headache of a new kind which is recurrent, persistent or severe, suspicion of thrombosis or infarction, significant rise in blood pressure or if jaundice occurs.

Caution should be exercised where there is the possibility of an interaction between a pre-existing disorder and a known or suspected side effect. The use of Noriday in women suffering from epilepsy, or with a history of migraine or cardiac or renal dysfunction may result in exacerbation of these disorders because of fluid retention. Caution should also be observed in women who wear contact lenses, women with impaired carbohydrate tolerance, depression, gallstones, a past history of liver disease, varicose veins, hypertension, asthma or any disease that is prone to worsen during pregnancy (e.g. multiple sclerosis, porphyria, tetany and otosclerosis).

Progestogen-only oral contraceptives may offer less protection against ectopic pregnancy, than against intrauterine pregnancy.

A meta-analysis from 54 epidemiological studies reported that there is a slightly increased relative risk of having breast cancer diagnosed in women who are currently using oral contraceptives (OC). The observed pattern of increased risk may be due to an earlier diagnosis of breast cancer in OC users, the biological effects of OCs or a combination of both. The additional breast cancers diagnosed in current users of OCs or in women who have used OCs in the last ten years are more likely to be localised to the breast than those in women who never used OCs.

Breast cancer is rare among women under 40 years of age whether or not they take OCs. Whilst the background risk increases with age, the excess number of breast cancer diagnoses in current and recent progesterone-only pill (POP) users is small in relation to the overall risk of breast cancer, possibly of similar magnitude to that associated with combined OCs. However, for POPs, the evidence is based on much smaller populations of users and so is less conclusive than that for combined OCs.

The most important risk factor for breast cancer in POP users is the age women discontinue the POP; the older the age at stopping, the more breast cancers are diagnosed. Duration of use is less important and the excess risk gradually disappears during the course of the 10 years after stopping POP use, such that by 10 years there appears to be no excess.

The evidence suggests that compared with never-users, among 10,000 women who use POPs for up to 5 years but stop by age 20, there would be much less than 1 extra case of breast cancer diagnosed up to 10 years afterwards. For those stopping by age 30 after 5 years use of the POP, there would be an estimated 2-3 extra cases (additional to the 44 cases of breast cancer per 10,000 women in this age group never exposed to oral contraceptives). For those stopping by age 40 after 5 years use, there would be an estimated 10 extra cases diagnosed up to 10 years afterwards (additional to the 160 cases of breast cancer per 10,000 never-exposed women in this age group).

It is important to inform patients that users of all contraceptive pills appear to have a small increase in the risk of being diagnosed with breast cancer, compared with non-users of oral contraceptives, but this has to be weighed against the known benefits.

Noriday contains lactose monohydrate. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine.

Depressed mood and depression are well-known undesirable effects of hormonal contraceptive use (see section 4.8). Depression can be serious and is a well-known risk factor for suicidal behaviour and suicide. Women should be advised to contact their physician in case of mood changes and depressive symptoms, including shortly after initiating the treatment.

4.5. Interaction with other medicinal products and other forms of interaction

The herbal remedy St John's wort (Hypericum perforatum) should not be taken concomitantly with this medicine as this could potentially lead to a loss of contraceptive effect.

Some drugs may modify the metabolism of Noriday reducing its effectiveness; these include certain sedatives, antibiotics, and antiepileptics. During the time such agents are used concurrently, it is advised that an alternative method of contraception, such as a condom, is also used.

The serum levels of prednisone, prednisolone, cloprednol and possibly other corticosteroids are considerably increased in those taking oral contraceptives. Both the therapeutic and toxic effects may be expected to increase accordingly.

4.6. Fertility, pregnancy and lactation

Pregnancy

Noriday is not indicated during pregnancy. If pregnancy occurs during medication with Noriday, treatment should be withdrawn immediately. Like all norethisterone derivatives used for contraception, Noriday has slight androgenic activity. At doses higher than normally used in OC and HRT formulations, masculinisation of female foetuses has been observed. The results of most epidemiological studies to date relevant to inadvertent foetal exposure to combinations of oestrogens with progestogens, indicate no teratogenic or foetotoxic effects.

Breast-feeding

There is no evidence that Noriday tablets diminish the yield of breast milk. Small amounts of steroid materials appear in the milk; their effect on the breast-fed child has not been determined.

4.7. Effects on ability to drive and use machines

Not relevant.

4.8. Undesirable effects

The incidence of side effects in clinical trials was lower than that experienced with oestrogen-containing oral contraceptives. Side effects which did occur included some cycle irregularity during the first few months of therapy, spotting or breakthrough bleeding, amenorrhoea, breast discomfort, gastrointestinal symptoms, rash, headaches, migraine, depression, fatigue, nervousness, disturbance of appetite and changes in weight, hepatic adenoma and libido.

Hypertension, which is usually reversible on discontinuing treatment, has occurred in a small percentage of women taking oral contraceptives.

Menstrual pattern: Women taking Noriday for the first time should be informed that they may initially experience menstrual irregularity. This may include amenorrhoea, prolonged bleeding and/or spotting but such irregularity tends to decrease with time. If a woman misses two consecutive periods, pregnancy should be ruled out before continuing the contraceptive regimen.

Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

4.9. Overdose

Serious ill effects have not been reported following acute ingestion of large doses of oral contraceptives by young children. Overdosage may be manifested by nausea, vomiting, breast enlargement and vaginal bleeding. There is no specific antidote and treatment should be symptomatic. Gastric lavage may be employed if the overdose is large and the patient is seen sufficiently early (within four hours).

🇵🇱 Known in Poland as

Medicines sold in Poland with the same active substance: W Polsce znany jako

  • Primolut-NorNorethisteroni acetas · taken by mouth

Same active substance. The strength, the form and whether you need a prescription can differ. Always ask a pharmacist before you switch. Polish medicines in the UK →

💬 Ask about this leaflet

Ask anything about Noriday 350 microgram Tablets. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.

Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.

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