Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Naseptin Nasal Cream
⚠ This medicine appears to have been discontinued
The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.
If you were prescribed this medicine, other products containing Chlorhexidine dihydrochloride, Neomycin sulfate may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.
What it is and what it is used for
for Naseptin contains an antibiotic and a disinfectant. Naseptin is used to treat and prevent infections in the nose. Naseptin works by killing certain bacteria that cause infections.
What you need to know before you take it
e Naseptin Do not use Naseptin:
- if you are allergic (hypersensitive) to chlorhexidine dihydrochloride, neomycin sulfate or any of the other ingredients of this medicine (listed in Section 6). Warnings and precautions Talk to your doctor or pharmacist before using Naseptin If you have hearing problems, it is important that you speak to your doctor before using Naseptin. Naseptin could make your hearing worse.
Naseptin PIL UK 013
Also, before you use Naseptin, tell your doctor if:
- you are elderly
- the patient is a child. If any of the above applies to you, or if you are not sure, speak to your doctor or pharmacist before you use Naseptin. Do not use Naseptin immediately after washing your face If Naseptin is mixed with certain soaps, it may not work properly. Avoid getting Naseptin onto your clothes or other fabrics If this happens, do not use bleach to remove it, as brown stains may develop. Other medicines and Naseptin Please tell your doctor or pharmacist if you are taking or have recently taken/used any other medicines, including medicines obtained without a prescription. Pregnancy and breast-feeding Naseptin is unlikely to have any effect on your unborn baby or on breast-feeding. Ask your doctor or pharmacist for advice before taking any medicine. Important information about some of the ingredients of Naseptin This product contains cetostearyl alcohol which may cause local skin reactions, for example contact dermatitis.
How to take it
Naseptin Always use Naseptin exactly as your doctor has told you to. You should check with your doctor or pharmacist if you are not sure. Place a small amount of the cream on the tip of your little finger and carefully apply inside one nostril. Repeat for the other nostril. Preventing infections Use Naseptin twice a day to prevent infection. Treating infections Use Naseptin 4 times a day to treat infection. Treatment is usually for 10 days. The amount you should use is the same for children, adults and the elderly. Naseptin is only to be used inside your nose. Do not use it in your eyes or ears.
Naseptin PIL UK 013
If you take more Naseptin than you should If you accidentally use too much cream, or someone else uses or swallows any of the cream, you should tell your doctor at once or contact your nearest accident and emergency department. Show any left-over cream or the empty container to the doctor. If you forget to use Naseptin If you forget to apply a dose, apply it as soon as possible, unless it is almost time to apply the next dose. Then go on as before. Do not apply a double dose. If you have any further questions on the use of this product, ask your doctor or pharmacist. 4. Possible side effects Do not worry. Like all medicines, Naseptin can cause side effects, although not everyone gets them. Naseptin sometimes causes the following side effects in some people: Tell your doctor or contact your nearest hospital straight away if you notice or suspect any of the following symptoms. You may need urgent medical treatment.
- Signs of a severe allergic reaction such as:
- swelling of the face, tongue or throat
- difficulty breathing
- dizziness
- severe irritation, reddening or blistering of your skin. Other possible side effects include:
- irritation of the skin
- hearing problems
- kidney problems (pain when you pass water, blood in your urine)
- if you use Naseptin for a long time, it may cause allergic skin reactions (redness or itching)
- temporary loss of your sense of smell or taste
- change of skin colour at the application site. If they are severe or last for more than a few days, tell your doctor. Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report
Possible side effects
directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By Naseptin PIL UK 013
reporting side effects you can help provide more information on the safety of this medicine.
How to store it
Naseptin Keep this medicine out of the sight and reach of children. Do not use Naseptin after the expiry date which is stated on the tube. The expiry date refers to the last day of that month. Do not store Naseptin above 25oC. Keep the tube tightly closed. Do not use Naseptin if you notice a change in the colour or feel of the cream. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist on how to dispose of medicines no longer required. These measures will help protect the environment.
Contents of the pack and other information
What Naseptin contains The active ingredients in this medicine are chlorhexidine dihydrochloride 0.1% w/w and neomycin sulfate 0.5% w/w. The other ingredients are medium-chain triglycerides, cetostearyl alcohol/ethylene oxide condensate, cetostearyl alcohol and water. What Naseptin looks like and contents of the pack Naseptin is a smooth, white cream. Naseptin comes in aluminium tubes of 15g (grams). Marketing Authorisation Holder and Manufacturer The product licence holder is: Alliance Pharmaceuticals Limited, Avonbridge House, Chippenham, Wiltshire, SN15 2BB, UK. Naseptin is manufactured by: FAMAR A.V.E. Avlon Plant, 49th km National Road Athens – Lamia, Avlona Attiki, 19011, Greece. The information in this leaflet applies only to Naseptin. If you have any questions or you are not sure about anything, ask your doctor or a pharmacist. This leaflet was last revised in: November 2024 Naseptin is a registered trademark of Alliance Pharmaceuticals Limited.
Naseptin PIL UK 013
Alliance and associated devices are registered Trademarks of Alliance Pharmaceuticals Limited. © Alliance Pharmaceuticals Limited 2024.
Naseptin PIL UK 013
Frequently asked questions about Naseptin Nasal Cream
How do I take Naseptin Nasal Cream?
Naseptin Nasal Cream comes as cream. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
What is the active substance in Naseptin Nasal Cream?
The active substance in Naseptin Nasal Cream is chlorhexidine dihydrochloride, neomycin sulfate.
Where does this information come from?
This leaflet reproduces the patient information leaflet approved for Naseptin Nasal Cream, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Can I get Naseptin Nasal Cream without a prescription?
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
About this leaflet
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
- Source: electronic medicines compendium (emc), Datapharm
- Active substance: chlorhexidine dihydrochloride, neomycin sulfate
- Official document: view the original leaflet on emc →
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
4.1. Therapeutic indications
Eradication of nasal infection with, and carriage of, Staphylococci.
4.2. Posology and method of administration
For nasal application only.
A small amount of Naseptin is placed on the little finger and applied to the inside of each nostril.
For prophylaxis: Naseptin is applied as above, twice daily, to prevent patients from becoming carriers and to inhibit the dispersion of Staphylococci.
For eradication of infection: Naseptin is applied four times daily for 10 days to eliminate organisms from the nares.
Children and elderly patients: There are no special dosage recommendations for either children or elderly patients.
4.3. Contraindications
Patients who have previously shown a hypersensitivity reaction to neomycin or chlorhexidine, although such reactions are extremely rare.
Hypersensitivity to the active substances or to any of the excipients listed in section 6.1.
4.4. Special warnings and precautions for use
For nasal application only. Keep out of the eyes and ears.
Irritative skin reactions can occasionally occur. Prolonged use of neomycin can lead to skin sensitisation, ototoxicity and nephrotoxicity. Use with caution in children, elderly patients and patients with impaired hearing (see Section 4.8 'Undesirable effects').
This medicinal product contains cetostearyl alcohol which may cause local skin reactions (e.g., contact dermatitis).
4.5. Interaction with other medicinal products and other forms of interaction
None known.
4.6. Pregnancy and lactation
Chlorhexidine and neomycin cannot be detected in the blood following application of Naseptin and its use is unlikely to have any effect on the foetus or on breast feeding.
4.7. Effects on ability to drive and use machines
None known.
4.8. Undesirable effects
Tabulated list of adverse reactions
Undesirable effects are listed by MedDRA System Organ Classes.
Assessment of undesirable effects is based on the following frequency groupings:
Very common: ≥1/10
Common: ≥1/100 to <1/10
Uncommon: ≥1/1,000 to <1/100
Rare: ≥1/10,000 to <1/1,000
Very rare: <1/10,000
Not known: cannot be estimated from the available data
System Organ Class
Frequency
Undesirable Effect
Immune system disorders
Not known
• anaphylaxis
Nervous system disorders
Not known
• temporary hyposmia
• temporary ageusia
Ear and labyrinth disorders
Not known
• ototoxicity1
Skin and subcutaneous tissue disorders
Not known
• Irritative skin reactions
• skin sensitisation
Renal and urinary disorders
Not known
• nephrotoxicity
General disorders and administration site conditions
Not known
• application site discolouration
1Use with caution in children, elderly patients and patients with impaired hearing (see Section 4.4 'Special warnings and precautions for use').
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
4.9. Overdose
Accidental ingestion of the contents of a Naseptin tube is unlikely to have any adverse effects on the patient.
🇷🇴 Known in Romania as
Medicines sold in Romania with the same active substance: Cunoscut în România ca
⚠ Not the same combination. This medicine contains Chlorhexidine dihydrochloride, Neomycin sulfate. The products below do not contain exactly the same set of active substances — they are not direct substitutes.
⚠ Same active substance, but a different pharmaceutical form (for example a gel instead of a tablet). Not interchangeable — ask a pharmacist.
- CORSODYL MINT MOUTHWASH 2 mg/ml over the counter partial — not the same combinationCHLORHEXIDINUM · taken by mouth
Some of these do not contain exactly the same active substances — check each one. The strength, the form and whether you need a prescription can differ. Always ask a pharmacist before you switch. Romanian medicines in the UK →
🇵🇱 Known in Poland as
Medicines sold in Poland with the same active substance: W Polsce znany jako
⚠ Not the same combination. This medicine contains Chlorhexidine dihydrochloride, Neomycin sulfate. The products below do not contain exactly the same set of active substances — they are not direct substitutes.
- Neomycinum Jelfa partial — not the same combinationNeomycini sulfas · eye / ear / nose
Some of these do not contain exactly the same active substances — check each one. The strength, the form and whether you need a prescription can differ. Always ask a pharmacist before you switch. Polish medicines in the UK →
💬 Ask about this leaflet
Ask anything about Naseptin Nasal Cream. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.