Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Indoramin 20 mg Tablet
⚠ This medicine appears to have been discontinued
The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.
If you were prescribed this medicine, other products containing Indoramin hydrochloride may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.
What it is and what it is used for
for
Indoramin 20mg Tablets (called 'Indoramin' throughout this leaflet) contain a medicine called indoramin (as indoramin hydrochloride). This belongs to a group of medicines called 'alpha-blockers' (also called alpha adrenoceptor antagonists). What Indoramin is used for A condition where your prostate becomes bigger, called 'benign prostatic hyperplasia' or BPH. The prostate is a gland found underneath the bladder in men. It surrounds the tube (called the urethra) which carries urine from the bladder to the outside of the body. If the prostate gland becomes bigger, it may squeeze on the urethra and make it hard for you to pass urine. When your prostate grows:
- the flow of your urine may be weaker or you may have to pass urine more often than before
- this can happen during the day or you can find you have to get up more often during the night
- you may have to wait for the flow of your urine to start
- you may find it difficult to stop the flow of your urine completely As men get older their prostate grows in size and some men will suffer these symptoms.
Patients who do not need or want an operation and also for patients waiting for an operation.
How Indoramin works Indoramin relaxes muscles in your bladder, prostate gland and the tube that carries urine from the bladder to the outside of the body this will help your urine flow better.
2.
What you need to know before you take it
e Indoramin
Do not take Indoramin if you: are allergic to Indoramin or any of the ingredients of this medicine (listed in Section 6) have heart failure
are taking monoamine oxidase inhibitors, sometimes called 'MAOIs', used for depression (see Other
medicines and Indoramin).
Warnings and precautions Talk to your doctor or pharmacist before taking Indoramin if you have: liver or kidney problems Parkinson's disease epilepsy ever had depression.
If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Indoramin. You may need to be given another medicine or your dose may need to be lowered. Other medicines and Indoramin Please tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines. This includes medicines obtained without a prescription, including herbal preparations. This is because Indoramin can affect the way some other medicines work. Also some other medicines can affect the way Indoramin works. In particular tell your doctor or pharmacist if you are taking any of the following medicines: monoamine oxidase inhibitors, sometimes called 'MAOIs', used for depression. Do NOT take Indoramin if you are already taking a MAOI medicines used for high blood pressure such as water tablets (diuretics) or beta-blockers medicines that can lower blood pressure such as water tablets (diuretics), moxisylytes (medicines used for circulation problems) and medicines used for depression, anxiety or to help you sleep medicines that may make you sleepy such as pain killers, antidepressants, tablets for your nerves and antihistamines. Cataract eye surgery patients If you are due to have eye surgery because of a cataract (cloudiness of the lens): Tell your eye specialist before the operation that you are using or have previously used Indoramin Indoramin and other medicines of the same type (alpha-blockers) may cause problems during the surgery which can be managed if your specialist is told before your operation. Indoramin with alcohol Do NOT drink alcohol if Indoramin makes you feel drowsy. Alcohol can increase the amount of Indoramin that gets from your stomach into your blood stream. This could make you feel more drowsy. Pregnancy and breast-feeding Occasionally a doctor may prescribe Indoramin for a woman. If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Driving and using machines You may feel sleepy while taking Indoramin. If this happens, do NOT drive or use any tools or machines. If you feel very sleepy, tell your doctor. Indoramin contains lactose Indoramin contains lactose (a type of sugar). If you have been told by your doctor that you have an intolerence to some sugars, contact your doctor before taking this medicinal product.
3.
How to take it
Indoramin
Always take Indoramin exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. How much to take The recommended dose is one tablet (20 mg) twice a day. The tablet should be swallowed with water. Some elderly patients may need just one tablet at night. Your doctor may increase your dose to a maximum total daily dose of 100 mg. Do NOT take more than your doctor has recommended. If you take more Indoramin than you should If you take more Indoramin than you should, contact your doctor or nearest hospital emergency department immediately. Take the container and any remaining tablets with you. Symptoms of overdose have included deep sedation leading to coma, irregular heartbeat, changes to your heartbeat (these symptoms can have potentially serious, life-threatening consequences), abnormally low blood pressure and fits. If you forget to take Indoramin If you forget to take a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do NOT take a double dose to make up for a forgotten dose. If you stop taking Indoramin Do not stop taking Indoramin without talking to your doctor. If you stop taking your tablets, your symptoms may come back. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine: when you start taking Indoramin you may feel sleepy. This will usually go after a few days. Other less common side effects include dry mouth, stuffy nose, weight gain, dizziness, failure to ejaculate, depression, headache and dizziness caused by low blood pressure, which can occur on standing. The dizziness may or may not be accompanied by fainting. Rare side effects (affects less than 1 in 1,000 people) allergic (hypersensitivity) reactions, such as a rash and itching Parkinson's disease may get worse. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard By reporting side effects you can help provide more information on the safety of this medicine.
5.
How to store it
Indoramin
Keep out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and blister. The expiry date refers to the last day of the month. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment 6.
Contents of the pack and other information
What Indoramin contains
- The active ingredient is indoramin (as indoramin hydrochloride). Each film-coated tablet contains indoramin hydrochloride equivalent to 20 mg of indoramin base.
- The other ingredients are lactose monohydrate, microcrystalline cellulose, magnesium stearate, polacrillin potassium and opadry yellow 02B520014 which consists of hypromellose, titanium dioxide (E171), polyethylene glycol, yellow iron oxide (E172) and black iron oxide (E172). What Indoramin looks like and contents of the pack Indoramin 20mg Tablets are pale yellow, triangular, biconvex film coated tablets which are embossed with key on both sides. This medicine comes in blister packs of 28, 30, 56, 60 & 84 tablets. Marketing Authorisation Holder & Manufacturer Brown & Burk UK Ltd 5 Marryat Close Hounslow West Middlesex TW4 5DQ United Kingdom.
This leaflet was last revised in 10/2025.
Frequently asked questions about Indoramin 20 mg Tablet
How do I take Indoramin 20 mg Tablet?
Indoramin 20 mg Tablet comes as tablet containing 20mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
What is the active substance in Indoramin 20 mg Tablet?
The active substance in Indoramin 20 mg Tablet is indoramin hydrochloride.
Are there equivalent medicines to Indoramin 20 mg Tablet?
Medicines with the same active substance, strength and form include: Doralese Tiltab Tablets 20 mg, Indoramin 20 mg film-coated tablets. They are interchangeable only if your prescriber or pharmacist says so.
Where does this information come from?
This leaflet reproduces the patient information leaflet approved for Indoramin 20 mg Tablet, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Can I get Indoramin 20 mg Tablet without a prescription?
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
About this leaflet
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
- Source: electronic medicines compendium (emc), Datapharm
- Active substance: indoramin hydrochloride
- Official document: view the original leaflet on emc →
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
4.1. Therapeutic indications
Indoramin is indicated in adults for conditions in which alpha blockade is indicated and the management of urinary outflow obstruction due to benign prostatic hyperplasia.
4.2. Posology and method of administration
Posology
Hyperplasia
Adults:
20 mg twice daily
Dosage may be increased in 20 mg increments at two-weekly intervals up to max. 100 mg per day if required.
Elderly:
20 mg at night may be adequate.
Paediatric population
Not recommended. There is no relevant use of indoramin in the paediatric population
Route of administration
Oral
4.3. Contraindications
Hypersensitivity to the active substance or to any of the excipients listed in section 6.1
Patients with established heart failure.
Patients already under treatment with a monoamine oxidase inhibitor.
4.4. Special warnings and precautions for use
Special warnings
Incipient cardiac failure should be controlled before treatment with indoramin.
Caution should be observed in prescribing indoramin for patients with hepatic or renal insufficiency.
A few cases of extrapyramidal disorders have been reported in patients treated with indoramin. Caution should be observed in prescribing indoramin in patients with Parkinson's disease.
In animals and in the one reported case of overdose in humans, convulsions have occurred. Due consideration should be given and great caution exercised in the use of indoramin in patients with epilepsy.
The 'Intraoperative Floppy Iris Syndrome' (IFIS, a variant of small pupil syndrome) has been observed during cataract surgery in some patients on or previously treated with tamsulosin. Isolated reports have also been received with other alpha-1 blockers and the possibility of a class effect cannot be excluded. As IFIS may lead to increased procedural complications during the cataract operation current or part use of alpha-1 blockers should be made known to the ophthalmic surgeon in advance of surgery.
Caution should be observed in prescribing indoramin for patients with a history of depression.
Clearance of indoramin may be affected in the elderly. A reduced dose, and/or reduced frequency of dosing may be sufficient in some elderly patients.
Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose -malabsorption should not take this medicine.
4.5. Interaction with other medicinal products and other forms of interaction
Do not use indoramin in patients being treated with a monoamine oxidase (MAO) inhibitor.
Concomitant use of indoramin with antihypertensive drugs or drugs with hypotensive properties e.g. antidepressants, anxiolytics, hypnotics and moxisylyte, may enhance their hypotensive action. Titration of dosage of the latter may therefore be needed.
Alcohol can increase both the rate and extent of absorption of indoramin, but no untoward effects have been reported at recommended doses.
4.6. Fertility, pregnancy and lactation
Pregnancy
Animal experiments indicate no teratogenic effects but indoramin tablets should not be prescribed for pregnant women unless considered essential by the physician.
Breast-feeding
There are no data available on the excretion of indoramin in human milk, but the drug should not be administered during lactation unless in the judgement of the physician such administration is clinically justifiable.
4.7. Effects on ability to drive and use machines
Drowsiness is sometimes seen in the initial stages of treatment with indoramin or when dosage is increased too rapidly. If drowsiness occurs, patients should be warned not to drive or operate machinery and to avoid CNS depressants including alcohol.
4.8. Undesirable effects
In general, indoramin is well tolerated.
The following undesirable effects have been observed and reported during treatment with indoramin with the following frequencies: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
MedDRA System Organ Class
Frequency
Undesirable effects
Immune system disorders
Rare
Hypersensitivity
Psychiatric disorders
Unknown
Depression
Nervous system disorders
Rare
Unknown
Parkinson's disease
Dizziness
Headache
Sedation or Drowsiness
Somnolence
Vascular disorders
Unknown
Hypotension, with or without syncope
Orthostatic hypotension (postural hypotension)
Respiratory, thoracic and mediastinal disorders
Unknown
Nasal congestion
Gastrointestinal disorders
Unknown
Dry mouth
Skin and subcutaneous tissue disorders
Rare
Rash
Pruritus
Reproductive system and breast disorders
Unknown
Ejaculation failure
General disorders and administration site conditions
Unknown
Fatigue
Investigation
Unknown
Weight increased
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
4.9. Overdose
Information available at present of the effects of acute overdosage in human beings with indoramin is limited. Effects seen have included deep sedation leading to coma, hypotension and fits.
In cases of overdose QTc prolongation can occur, sometimes complicated by severe arrhythmias, such as Torsades de Pointes.
Results of animal work suggest that hypothermia may also occur.
Suggested therapy is along the following lines:
1. Recent ingestion of large numbers of tablets would require gastric lavage or a dose of ipecacuanha to remove any of the product still in the stomach of the conscious patient.
2. Cardiac monitoring should be initiated immediately and continued for at least 24 hours.
3. Ventilation should be monitored and assisted if necessary.
4. Circulation support and control of hypotension should be maintained.
5. If convulsions occur diazepam may be tried.
Temperature should be closely monitored. If hypothermia occurs, rewarming should be carried out very slowly to avoid possible convulsions.
💬 Ask about this leaflet
Ask anything about Indoramin 20 mg Tablet. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.