Patient leaflets and SmPCs, drug interaction checker, official and paediatric dosages, pregnancy and breastfeeding guidance, and NHS pharmacy opening hours — all in one place.
Patient leaflets and SmPCs, drug interaction checker, official and paediatric dosages, pregnancy and breastfeeding guidance, and NHS pharmacy opening hours — all in one place.
Difflam contains the active substance benzydamine
agent.
Difflam is used in adults and children above 6 years of age for symptomatic local treatment for the relief of pain and irritation of the mouth and throat.
Do not take Difflam Lozenges: If you are allergic to benzydamine or any of the other ingredients of this medicine (listed in section 6). −
phenylketonuria. − If you are allergic to salicylic acid or to other
anti-inflammatory painkillers called NSAIDs (e. g. ibuprofen).
CODE: STX003926 DESCRIPTION: PierreFabre_Disch AG_Leaflet_ TantumVerde_160x250 mm DIE CUT/SUPPLIER: - SIZE: 160x250 mm
VERSION N°: 00 DATE: 05/07/2023 UNIT OF MEASUREMENT: mm
NOTES:
ARTWORK CREATION READABILITY REQUIREMENT PRINT EFFECT COLOR LIST HOLDER APPROVAL SIGNATURE
PRODUCT NAME: PIL.DIFFLAM ORANGE HONEY BLS UK DESIGN CODE: PSX010345 VERSION N°: 01 BRAILLE REFERENT: NA BRAILLE TEXT: NA
MINIMUM FONT SIZE pt: NA SPACE BETWEEN LINE pt:NA PICTOGRAMS:NA
NOTES:
Warning and precautions
Talk to your doctor or pharmacist before taking this medicine: − − If you have been told by your doctor that you
have an intolerance to some sugars, contact your doctor before taking this medicine. − If after using the lozenges the pain in
your mouth or throat gets worse or
fever or other symptoms, you should speak to your doctor or pharmacist.
Taking other medicines and Difflam Lozenges Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines, including medicines obtained without
Difflam Lozenges are not expected to affect other medicines, however if you are not sure, please ask your doctor or pharmacist about other medicines
Difflam Lozenges with food, drink Food and drink have no influence.
Pregnancy, breast-feeding If you are pregnant or breast-feeding, think you may
doctor or pharmacist for advice before taking this medicine.
You should not use Difflam during pregnancy unless clearly necessary and advised by your doctor. If you need treatment the lowest dose for the shortest time possible should be used. Difflam lozenges should not be used during breast-feeding.
Driving and using machines Difflam Lozenges does not affect your ability to drive or use machines.
Difflam Lozenges contains Isomalt told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Sunset yellow (E 110): may cause allergic reactions.
Fragrance with Citral, Citronellol, d-Limonene, Geraniol, Linalool. These may cause allergic reactions.
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
11 JUL 2025 09:39
(for client out of DAM Sistem only) This design is 'property' of Angelini Pharma S.p.A and must not be delivered or exhibited to another person in original or in copy.
The recommended dose is:
per day. Use in children
should be administered under an adult supervision.
be given Difflam Lozenges. Let one lozenge dissolve slowly in your mouth up
Do not swallow. Do not chew.
If after using the lozenges your throat gets worse or does not feel better, speak to your pharmacist or doctor. If you take more Difflam Lozenges than you should If you accidentally take too many lozenges, you should contact your pharmacist, doctor or nearest hospital casualty department immediately. Always take the labelled medicine package with you, whether there are any lozenges left or not.
Like all medicines, this medicine can cause side- effects, although not everybody gets them. Allergic reactions are rare but can be serious. Tell your doctor immediately if you get any sudden swelling in the mouth/throat, difficulty breathing, rash or itching especially if affecting the whole body. Uncommon
• sunburn).
• Burning sensation or dryness of the mouth. If
to reduce the effect. Very rare
• Sudden swelling in the mouth/throat and mucous membranes (angioedema). • Difficulty breathing (laryngospasm). Not known (frequency cannot be estimated from the available data): • Local loss of sensitivity of the oral mucosa (hypaesthesia oral) • Allergic reaction (Hypersensitivity) • Serious allergic reaction (anaphylactic shock), signs of which may include difficulty breathing, chest pain or chest tightness, and/ or feeling dizzy/faint, severe itching of the skin or raised lumps on the skin, swelling of the face, lips, tongue and /or throat, and which may be potentially life-threatening.
Reporting of side effects If you get any the side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme (www.mhra.go.uk/yellowcard). By reporting side effects you can help provide more information on the safety of this medicine.
benzydamine). • The other ingredients are isomalt (E 953), acesulfame potassium, citric acid monohydrate, orange flavour, honey flavour, levomenthol, quinoline yellow (E 104), sunset yellow (E 110). What Difflam Lozenges looks like and contents of the pack Difflam Lozenges are orange-yellow, square
lozenges can be packaged in
Not all pack sizes may be marketed Marketing Authorisation Holder and Manufacturer The Marketing Authorisation Holder is Cooper Consumer Health B.V. Verrijn Stuartweg 60, 1112AX Diemen – Netherlands The Manufacturer is: A. C.R. A.F. S.p. A., Via Vecchia del Pinocchio, 22 60131 – Ancona, Italy This leaflet was last revised in April 2026
Difflam 3 mg Lozenge Orange Honey Flavour comes as medicine containing 3 mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
The active substance in Difflam 3 mg Lozenge Orange Honey Flavour is benzydamine hydrochloride.
Medicines with the same active substance include: Benzydamine 0.15% w/v Mouthwash, Benzydamine 0.15%w/v Oromucosal Spray, Benzydamine Hydrochloride 0.15 % w/v Oromucosal Spray, Benzydamine Hydrochloride 0.15% w/v Oromucosal solution spray. They are interchangeable only if your prescriber or pharmacist says so.
This leaflet reproduces the patient information leaflet approved for Difflam 3 mg Lozenge Orange Honey Flavour, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
Ask anything about Difflam 3 mg Lozenge Orange Honey Flavour. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.
We use essential cookies to make the site work. We would also like to set optional cookies to understand how the site is used, so we can improve it. We will not set optional cookies unless you accept. See our cookie policy and privacy policy.