Pharmacy Guide

Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.

Pharmacy Guide

Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.

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Celluvisc 1.0% w/v Eye drops, solution, unit dose

⚠ This medicine appears to have been discontinued

The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.

If you were prescribed this medicine, other products containing Carmellose sodium may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.

Active substance: Carmellose sodium

Equivalent medicines (same active substance, strength and form)

Source: electronic medicines compendium (emc)
Official leaflet: Read the PIL on emc

What it is and what it is used for

for

Celluvisc is a substitute for tears and contains the lubricant called carmellose sodium. It is used for the treatment of the symptoms of dry eye (such as soreness, burning, irritation or dryness) caused by not producing enough tears to keep the eye wet. 2.

What you need to know before you take it

e Celluvisc

Do not use Celluvisc If you are allergic (hypersensitive) to carmellose sodium or any of the other ingredients of this medicine (listed in section 6). Warnings and precautions • • •

If you wear contact lenses, these should be removed before using Celluvisc. The lenses can be put back again 15 minutes after you have applied your drops. If irritation, pain, redness or changes in vision occur or if you feel your condition is getting worse, stop taking this medicine and consult your doctor or pharmacist. To avoid contamination or possible eye injury, do not let the open-end of the single-dose container touch your eye or anything else.

Other medicines and Celluvisc Please tell your doctor or pharmacist if you are using, have recently used or might use any other medicines, including medicines obtained without a prescription. If you are using other eye drops, leave at least 15 minutes between putting in the other eye drops and Celluvisc.

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Pregnancy and breast-feeding Celluvisc can be used during pregnancy and breast-feeding. Driving and using machines Celluvisc may cause short-lasting blurring of vision typically lasting 1 – 15 minutes. If you do experience temporary blurring, do not drive or use machines until your sight is clear. 3.

How to take it

Celluvisc

Celluvisc is for ocular use (applied in the eye). Always use this medicine exactly as described in this leaflet or as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure. The recommended dose is 1-2 drops of Celluvisc in the affected eye/eyes as needed. Make sure that the single-dose container is intact before use. The solution should be used immediately after opening. Wash your hands before use.

1. 2. 3.

Tear one single-dose container from the strip. Hold the single-dose container upright (with the cap uppermost) and twist-off the cap. Gently pull down the lower eyelid to form a pocket. Turn the single-dose container upside down and squeeze it to release one drop into each eye. Blink your eyes a few times.

Do not re-use the single-dose container even if there is some solution left. It is most important that you throw it away and do not keep it. If you use more Celluvisc than you should It will not cause you any harm. If you are worried, talk to your doctor or pharmacist. If you forget to use Celluvisc Apply your next dose as required or at the normal time as directed by your pharmacist or doctor. Do not take a double dose to make up for forgotten individual doses. If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse. 4.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. The following adverse reactions or medically relevant adverse events were reported during clinical trials:

2

Common (may affect up to 1 in 10 people)

  • eye irritation (including burning and discomfort)
  • eye pain
  • itchy eyes
  • visual disturbance Post-Marketing Data The following adverse reactions or medically relevant adverse events have been reported since the drug has been marketed: Uncommon (may affect up to 1 in 100 people)
  • allergic reactions (including eye or eyelid swelling)
  • blurring of vision
  • increase in tear production (also known as tearing)
  • sticky eye
  • crusting of the eyelid and/or drug residue
  • a feeling that something is in your eye
  • redness of the eye/eyelid
  • eyesight worsening
  • eye injury to the surface of the eye due to the tip of the vial touching the eye during use Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine. 5.

How to store it

Celluvisc

Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the single-dose container tab, the foil pouch and the carton after EXP. The expiry date refers to the last day of that month. Do not store above 25°C. Keep the single dose containers in the pouch and place the pouch back in the outer carton. Pouch is required to prevent moisture loss. Do not use if the packaging shows evidence of tampering. Do not use if solution changes colour or becomes cloudy. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment. 6.

Contents of the pack and other information

What Celluvisc contains • •

The active substance is carmellose sodium 10 mg/ml. The other ingredients are sodium chloride, sodium lactate, potassium chloride, calcium chloride dihydrate and purified water.

The ingredients used in Celluvisc were chosen to match what appears in tears produced naturally by the eye.

3

What Celluvisc looks like and contents of the pack Celluvisc is an eye drop solution. It is presented as a clear, colourless to pale yellow solution in a small see-through (bubble-like) casing (known as a 'single-dose container'). The single-dose container has a twist-off cap. Each single-dose container contains 0.4 ml of solution. Each pack contains 10, 20, 30, 40, 60 or 90 foil-pouched single-dose containers. Each foil pouch contains 10 single-dose containers. Not all pack sizes may be marketed. Marketing Authorisation Holder AbbVie Ltd. Maidenhead SL6 4UB UK Tel: +44 (0)1628 561090 Manufacturer Allergan Pharmaceuticals Ireland Castlebar Road Westport County Mayo Ireland This leaflet was last revised in 01/2025.

To listen to or request a copy of this leaflet in Braille, large print or audio please contact the Marketing Autorisation Holder.

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Frequently asked questions about Celluvisc 1.0% w/v Eye drops, solution, unit dose

How do I take Celluvisc 1.0% w/v Eye drops, solution, unit dose?

Celluvisc 1.0% w/v Eye drops, solution, unit dose comes as eye drops. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.

What is the active substance in Celluvisc 1.0% w/v Eye drops, solution, unit dose?

The active substance in Celluvisc 1.0% w/v Eye drops, solution, unit dose is carmellose sodium.

Are there equivalent medicines to Celluvisc 1.0% w/v Eye drops, solution, unit dose?

Medicines with the same active substance, strength and form include: Celluvisc 0.5% w/v, eye drops, solution, unit dose. They are interchangeable only if your prescriber or pharmacist says so.

Where does this information come from?

This leaflet reproduces the patient information leaflet approved for Celluvisc 1.0% w/v Eye drops, solution, unit dose, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.

Can I get Celluvisc 1.0% w/v Eye drops, solution, unit dose without a prescription?

Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.

About this leaflet

The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.

Medical disclaimer: This page is for information only and does not replace advice from your doctor or pharmacist. Always read the leaflet supplied with your medicine. If you are unwell, call NHS 111; in an emergency, call 999.

Medicines with the same active substance: Carmellose sodium (2 medicines)
See every medicine containing this substance, or browse the full A–Z of active substances.
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
Technical information intended for healthcare professionals (doctors and pharmacists). The Summary of Product Characteristics (SmPC) is the official document approved by the MHRA/EMA. It does not replace the patient leaflet or a doctor’s advice.

4.1. Therapeutic indications

Treatment of the symptoms of dry eye.

4.2. Posology and method of administration

Instil one or two drops in the affected eye/s as needed.

Ensure that the single-dose container is intact before use. The eye drop solution should be used immediately after opening.

Concomitant ocular medication should be administered 15 minutes apart from the instillation of Celluvisc.

Paediatric population

The safety and efficacy of Celluvisc in Paediatric population have not been established. No data are available.

4.3. Contraindications

Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.

4.4. Special warnings and precautions for use

If irritation, pain, redness and changes in vision occur or worsen, treatment should be discontinued and a new assessment considered.

Contact lenses should be removed before each application and may be inserted after 15 minutes.

To avoid contamination or possible eye injury, do not touch the tip of the vial to any surface and avoid contact with the eye. Discard open single dose container after use.

4.5. Interaction with other medicinal products and other forms of interaction

None known.

For the use of concomitant ocular products, see section 4.2.

4.6. Fertility, pregnancy and lactation

Pregnancy and Breast-feeding

Due to the negligible systemic exposure and the lack of pharmacological activity Celluvisc can be used during pregnancy and breast-feeding.

4.7. Effects on ability to drive and use machines

Celluvisc has minor or moderate influence on the ability to drive and use machines as it may cause transient blurring of vision which may impair the ability to drive or operate machines. Do not drive or use machinery unless vision is clear.

4.8. Undesirable effects

The frequency of adverse reactions documented during clinical trials is defined as follows:

Very Common (≥1/10)

Common (≥1/100,<1/10)

Uncommon (≥1/1000,<1/100)

Rare (≥1/10000, <1/1000)

Very Rare (<1/10000)

Not known (cannot be estimated from the available data).

Eye disorders:

Common: Eye irritation (including burning and discomfort), eye pain, eye pruritus, visual disturbance.

Postmarketing Experience

The following additional adverse reactions have been identified during postmarketing use of Celluvisc 1.0% in clinical practice.

Immune System Disorders

Uncommon: Hypersensitivity including eye allergy with symptoms of eye swelling or eyelid edema.

Eye Disorders

Uncommon: Lacrimation increased, vision blurred, eye discharge, eyelid margin crusting and/or medication residue, foreign body sensation in eye, ocular hyperemia, visual impairment.

Injury, Poisons and Procedural Complications

Uncommon: Superficial injury of eye (from the vial tip touching the eye during administration) and/or corneal abrasion

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via Yellow Card Scheme; Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

4.9. Overdose

Accidental overdose will present no hazard.

💬 Ask about this leaflet

Ask anything about Celluvisc 1.0% w/v Eye drops, solution, unit dose. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.

Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.

Medicines containing Carmellose sodium

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