Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Pharmacy Guide
Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.
Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets
⚠ This medicine appears to have been discontinued
The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.
If you were prescribed this medicine, other products containing Loratadine may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.
What it is and what it is used for
for
What Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets are Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets contains the active substance Loratadine which belongs to a group of medicines called antihistamines. How Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets work. Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets help to reduce your allergy symptoms by stopping the effects of a substance called "histamine", which is produced in the body when you are allergic to something. When Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets should be taken Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets relieves symptoms associated with allergic rhinitis (for example, hayfever), such as sneezing, runny or itchy nose, and burning or itchy eyes in adults and children over the age of 2 years who weigh more than 30 kg. Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets may also be used to help relieve symptoms of urticaria (itching and redness) which is often known as hives or nettle rash. The effect of Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets will last a whole day and should help you to continue your normal daily activities and sleep. You must talk to a doctor if you do not feel better or if you feel worse.
What you need to know before you take it
e Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets : Do not take Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets if: you are hypersensitive (allergic) to Loratadine, or any of the other ingredients of this medicine (listed in section 6). you are (or think you may be) pregnant, or are breastfeeding Warnings and precautions Talk to your doctor or pharmacist before taking Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets if: you have liver disease. You are scheduled to have any skin tests for allergies. Do not take Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets for two days before having these tests. This is because it may affect the test results. If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before taking Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets. Children Do not give Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets to children younger than 2 years old or to children 2 to 12 years old who weigh less than 30 kg. There are other formulations more suitable for children 2 to 12 years old who weigh less than 30 kg. Other medicines and Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets: Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed. The side effects of Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets may increase when used together with medicines that alter the performance of some enzymes responsible for drugmetabolism in the liver. However, in clinical studies, no increase in side effects of loratadine was seen with products that altered the performance of these enzymes. Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets with food, drink and alcohol: Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets should not be affected by food or drink. You do not have to avoid alcohol whilst taking this medicine. Pregnancy If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. As a precautionary measure, it is preferable to avoid the use of Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets during pregnancy. Breast-feeding Ask your doctor or pharmacist for advice before taking any medicine. This medicine should not be taken by women who are breastfeeding because the active ingredient, Loratadine, passes into breast milk.
Driving and using machines: In clinical trials that assessed driving ability, no impairment was observed in patients receiving loratadine. At the recommended dose, Brown & Burk Once-A-Day Hayfever & Allergy 10mg tablets are not expected to cause you to be drowsy or less alert. However, very rarely some people experience drowsiness, which may affect their ability to drive or use machines. Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets contains lactose. Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets contains lactose; thus if you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
How to take it
Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets: Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. The score line of the tablet is only there to help you break the tablet if you have difficulty swallowing it whole. The following section contains instructions on how many tablets to take and when. Do not exceed the dose stated below. Adults, the elderly, children aged 12 years and over: One tablet to be swallowed once daily. Children aged 2 to 12 years: If the child weighs more than 30 kg, one tablet taken once daily is recommended. If the child weighs less than 30 kg, the 10mg strength tablet is not recommended. If you are unsure ask your doctor or pharmacist for advice. This medicine are not recommended in children under 2 years. If you take more Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets than you should: If you (or someone else) have accidentally taken more this medicine than you/they should, contact your doctor or pharmacist immediately, or go to the nearest Accident and Emergency hospital department. No serious problems are expected however, you may get a headache, have a rapid heartbeat or feel sleepy. If you forget to take Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets: Take your recommended dose as soon as you remember; wait at least 24 hours before taking another tablet. Do not take a 'double dose' to make up for missed doses. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The most commonly reported side effects in adults and children over 12 years of age are:
- drowsiness
- headache
- increased appetite
- difficulty sleeping. The most commonly reported side effects in children aged 2 to 12 years are:
- headache
- nervousness
- tiredness The following very rare side effects (may affect upto 1 in 10,000 people) have also been seen during the marketing of loratadine:
- severe allergic reaction (including swelling)
- dizziness
- convulsion
- fast or irregular heartbeat
- nausea (feeling sick)
- dry mouth
- upset stomach
- liver problems
- hair loss
- rash
- tiredness Not known (frequency cannot be estimated from the available data)
- weight increased Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5.
How to store it
Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets:
Keep this medicines out of the sight and reach of children. Your medicine may harm them.
There are no special storage recommendations for this medicine. However, do not store your medicine in a very damp or very hot place, such as the bathroom or kitchen.
Do not use after the expiry date stated on the outer carton/blister strip after EXP. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
If there is anything about this medicine you do not understand or are unsure about, your doctor or pharmacist will be able to help or advise you.
6.
Contents of the pack and other information
–
The active substance in your tablets is loratadine. Each this medicine contains 10mg of loratadine.
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The other ingredients in your tablets are lactose monohydrate, microcrystalline cellulose, maize starch, magnesium stearate.
This medicine are white or almost white, 8mm round, flat tablets, debossed with letter 'L' on one side and with a score line on other. This medicine are available in packs of 7, 14 and 30 tablets from your pharmacist. Marketing Authorisation Holder & Manufacturer Brown & Burk UK Ltd 5 Marryat Close Hounslow West Middlesex TW4 5DQ United Kingdom Marketing Authorisation Number PL 25298/0117 This leaflet was last revised in: April 2018
Frequently asked questions about Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets
How do I take Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets?
Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets comes as tablet containing 10mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.
What is the active substance in Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets?
The active substance in Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets is loratadine.
Are there equivalent medicines to Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets?
Medicines with the same active substance, strength and form include: Boots One-a-Day Allergy Relief 10mg Tablets (P & GSL), Clarityn Allergy 10mg Tablets (GSL), Clarityn Allergy 10mg Tablets (P). In total there are 6 equivalent products. They are interchangeable only if your prescriber or pharmacist says so.
Where does this information come from?
This leaflet reproduces the patient information leaflet approved for Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.
Can I get Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets without a prescription?
Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.
About this leaflet
The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.
- Source: electronic medicines compendium (emc), Datapharm
- Active substance: loratadine
- Official document: view the original leaflet on emc →
⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+
4.1. Therapeutic indications
This medicine is indicated for the symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria in adults and children over the age of 2 years with a body weight more than 30 kg.
4.2. Posology and method of administration
Posology
Adults and children over 12 years of age:
10 mg once daily (one tablet once daily). .
Paediatric population
Children 2 to 12 years of age are dosed by weight :
Body weight more than 30 kg: 10 mg once daily (one tablet once daily)
Body weight 30 kg or less: The 10 mg strength tablet is not appropriate in children with a body weight less than 30 kg. There are other formulations more suitable for children 2 to 12 years old with body weight 30 kg or less.
Efficacy and safety of this medicine in children under 2 years of age has not been established. No data are available.
Hepatic impairment
Patient with severe liver impairment should be administered a lower initial dose because they may have reduced clearance of loratadine. An initial dose of 10 mg every other day is recommended for adults and children weighing more than 30 kg,
Renal impairment
No dosage adjustments are required in patients with renal insufficiency.
Elderly
No dosage adjustments are required in the elderly.
Method of administration
Oral use. The tablet may be taken without regard to mealtime.
4.3. Contraindications
Hypersensitive to the active substance or to any of the excipients listed in section 6.1.
4.4. Special warnings and precautions for use
This medicine should be administered with caution in patients with severe liver impairment (see 4.2)
This medicinal product contains lactose; thus patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
The administration of this medicine should be discontinued at least 48 hours before skin tests since antihistamines may prevent or reduce otherwise positive reactions to dermal reactivity index.
4.5. Interaction with other medicinal products and other forms of interaction
When administered concomitantly with alcohol, this medicine has no potentiating effects as measured by psychomotor performance studies.
Potential interaction may occur with all known inhibitors of CYP3A4 or CYP2D6 resulting in elevated levels of loratadine (see Section 5.2), which may cause an increase in adverse events.
Increase in plasma concentrations of loratadine has been reported after concomitant use with ketoconazole, erythromycin, and cimetidine in controlled trials, but without clinically significant changes (including electrocardiographic).
Paediatric population
Interaction studies have only been performed in adults.
4.6. Fertility, pregnancy and lactation
Pregnancy
A large amount of data on pregnant women (more than 1000 exposed outcomes) indicate no malformative nor feto/ neonatal toxicity of loratadine. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity (see section 5.3).
As a precautionary measure, it is preferable to avoid the use of loratadine Tablets during pregnancy.
Breast-feeding
Loratadine is excreted in breast milk, therefore the use of loratadine is not recommended in breast-feeding women.
Fertility
There are no data available on male and female fertility.
4.7. Effects on ability to drive and use machines
In clinical studies that assessed driving ability, no impairment was observed in patients receiving loratadine. This medicine has no or negligible influence on the ability to drive and use machines. However, patients should be informed that very rarely some people experience drowsiness, which may affect their ability to drive or use machines.
4.8. Undesirable effects
Summary of the safety profile
In clinical trials involving adults and adolescents in a range of indications including allergic rhinitis (AR) and chronic idiopathic urticarial (CIU), at the recommended dose of 10 mg daily, adverse reactions with loratadine were reported in 2% of patients in excess of those treated with placebo. The most frequent adverse reactions reported in excess of placebo were somnolence (1.2%), headache (0.6%), increased appetite (0.5%) and insomnia (0.1%).
Tabulated list of adverse reactions
The following adverse reactions reported during the post-marketing period are listed in the following table by System Organ Class. Frequencies are defined as very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000) and not known (cannot be estimated from the available data).
Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness.
System Organ Class
Frequency
Adverse Experience Term
Immune system disorders
Very rare
Hypersensitivity reactions (including angioedema and anaphylaxis).
Nervous system disorders
Very rare
Dizziness, convulsion
Cardiac disorders
Very rare
Tachycardia, palpitation
Gastrointestinal disorders
Very rare
Nausea, dry mouth, gastritis
Hepato-bilary disorders
Very rare
Abnormal hepatic function
Skin and subcutaneous tissue disorders
Very rare
Rash, alopecia
General disorders and administration site conditions
Very rare
Fatigue
Investigations
Not known
Weight increased
Paediatric population
In clinical trials in a paediatric population, children aged 2 through 12 years, common adverse reactions reported in excess of placebo were headache (2.7%), nervousness (2.3%), and fatigue (1%).
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
4.9. Overdose
Overdosage with loratadine increased the occurrence of anticholinergic symptoms. Somnolence, tachycardia and headache have been reported with overdoses.
In the event of overdose, general symptomatic and supportive measures are to be instituted and maintained for as long as necessary. Administration of activated charcoal as a slurry with water may be attempted. Gastric lavage may be considered. Loratadine is not removed by haemodialysis and it is not known if loratadine is removed by peritoneal dialysis. Medical monitoring of the patient is to be continued after emergency treatment.
💬 Ask about this leaflet
Ask anything about Brown & Burk Once-A-Day Hayfever & Allergy 10mg Tablets. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.
Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.