What you need to know before you take it

e Boots Thrush Treatment 150 mg Capsule Do not take Boots Thrush Treatment 150 mg Capsule if you:

• are allergic to Fluconazole, to other medicines you have taken to treat fungal infections or to any of the other ingredients of this medicine (listed in section 6).
• are taking astemizole, terfenadine (antihistamine medicines for allergies)
• are taking cisapride (used for stomach upsets)
• are taking pimozide (used for treating mental illness)
• are taking quinidine (used for treating heart arrhythmia)
• are taking erythromycin (an antibiotic for treating infections)
• suffer from porphyria. Warnings and precautions Talk to your doctor, pharmacist or nurse before taking Fluconazole if you:
• are unsure about the cause of your symptoms
• have had thrush more than twice in the last six months
• or your partner have ever been exposed to a sexually transmitted disease
• are taking any medicine other than the contraceptive pill
• suffer from any chronic disease or illness
• are aged under 16 or over 60 years
• have had any disease or illness affecting the liver or kidneys, or have had any unexplained jaundice (yellowing of the skin and eyes)
• suffer from heart disease, including heart rhythm problems
• develop severe skin reactions (itching, reddening of the skin or difficulty in breathing)
• develop signs of 'adrenal insufficiency' where the adrenal glands do not produce adequate amounts of certain steroid hormones such as cortisol (chronic, or long lasting fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain)
• if the fungal infection does not improve, an alternative antifungal therapy may be needed
• have ever developed a severe skin rash or skin peeling, blistering and/or mouth sores after taking Boots Thrush Treatment 150 mg Capsule. Serious skin reactions including drug reaction with eosinophilia and systemic symptoms (DRESS) have been reported in association with Boots Thrush Treatment 150 mg Capsule. Stop taking Boots Thrush Treatment 150 mg Capsule and seek medical attention immediately if you notice any of the symptoms related to these serious skin reactions described in section 4. Women only:
• if you are pregnant, suspect you might be pregnant or are breast-feeding
• if you have any abnormal or irregular vaginal bleeding or a blood stained discharge
• if you have vulval or vaginal sores, ulcers or blisters
• if you are experiencing lower abdominal pain or burning on passing urine. Men only:
• if your sexual partner does not have

vaginal thrush

• if you have penile sores, ulcers or blisters
• if you have an abnormal penile discharge (leakage)
• if your penis has started to smell
• if you have pain on passing urine. Children (under 16 years): Paediatric use is not recommended. Other medicines and Boots Thrush Treatment 150 mg Capsule: Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. There are some medicines that may interact with Fluconazole. Make sure your doctor knows if you are taking any of the following medicines:
• rifampicin or rifabutin (antibiotics for infections)
• alfentanil, fentanyl (used as anaesthetic)
• amitriptyline, nortriptyline (used as anti-depressant)
• amphotericin B, voriconazole (anti-fungal)
• medicines that thin the blood to prevent blood clots (warfarin or similar medicines)
• benzodiazepines (midazolam, triazolam or similar medicines) used to help you sleep or for anxiety
• carbamazepine or phenytoin (used for treating fits)
• olaparib (used for treating ovarian cancer)
• nifedipine, isradipine, amlodipine, verapamil, felodipine and losartan (for hypertension – high blood pressure)
• ciclosporin, everolimus, sirolimus or tacrolimus (to prevent transplant rejection)
• cyclosphosphamide and vinca alkaloids (vincristine, vinblastine or similar medicines) used for treating cancer
• halofantrine (used for treating malaria)
• statins (atorvastatin, simvastatin and fluvastatin or similar medicines) used for reducing high cholesterol levels
• methadone (used for pain)
• celecoxib, flurbiprofen, naproxen, ibuprofen, lornoxicam, meloxicam, diclofenac (Non-Steroidal Anti-lnflammatory Drugs (NSAID))
• oral contraceptives
• prednisone (used to treat allergies)
• zidovudine, also known as AZT; saquinavir (used in HIV-infected patients)
• medicines for diabetes such as chlorpropamide, glibenclamide, glipizide or tolbutamide
• theophylline (used to control asthma)
• vitamin A (nutritional supplement)
• ivacaftor (used for treating cystic fibrosis)
• amiodarone (used for treating uneven heartbeats 'arrhythmias')
• hydrochlorothiazide (a diuretic)
• ibrutinib (used for treating blood cancer)
• tofacitinib (used for treating rheumatoid arthritis)
• lurasidone (used for treating schizophrenia and bipolar disorder)
• abrocitinib (used for treating atopic dermatitis)
• tolvaptan used to treat hyponatremia (low levels of sodium in your blood) or to slow kidney function decline. Pregnancy, breast-feeding and fertility If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. If you are planning to become pregnant, it is recommended to wait a week after a single dose of fluconazole before becoming pregnant. For longer courses of treatment with fluconazole, talk to our doctor on the need for appropriate contraception during treatment which should continue for one week after the last dose. You should not take Boots Thrush Treatment 150 mg Capsule if you are pregnant, think you may be pregnant, are trying to become pregnant or breast-feeding, unless your doctor has told you so. If you become pregnant while taking this medicine or within 1 week of the most recent dose, contact your doctor. Fluconazole taken during the first, or second trimester of pregnancy may increase the risk of miscarriage. Fluconazole taken at low doses during the first trimester may slightly increase the risk of a baby being born with birth defects affecting the bones and/or muscles. There have been reports of babies born with birth defects affecting the skull, ears, and bones of the thigh and elbow in women treated for three months or more with high doses (400-800 mg daily) of fluconazole for coccidioidomycosis. The link between fluconazole and these cases is not clear. Driving and using machines Boots Thrush Treatment 150 mg Capsule may occasionally cause dizziness or fits. If affected do not drive or use machinery. Boots Thrush Treatment 150 mg Capsule contains lactose If you have been told by your doctor that you have an intolerance to some sugars,

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• abnormal electrocardiogram (ECG), change in heart rate or rhythm
• hair loss. Not known: frequency cannot be estimated from the available data
• hypersensitivity reaction with skin rash, fever, swollen glands, increase in a type of white blood cell (eosinophilia) and inflammation of

How to take it

Boots Thrush internal organs (liver, lungs, heart, Treatment 150 mg Capsule kidneys and large intestine) (Drug Always take this medicine exactly as Reaction or rash with Eosinophilia described in this leaflet or as your and Systemic Symptoms (DRESS). doctor, pharmacist or nurse has told Reporting of side effects you. Check with your doctor, If you get any side effects, talk to your pharmacist or nurse if you are not sure. doctor, pharmacist or nurse. This You should read the instructions on the includes any possible side effects not listed in this leaflet. You can also report pack. Boots Thrush Treatment 150 mg side effects directly via the Yellow Card Capsule should only be taken by Scheme at: mouth. www.mhra.gov.uk/yellowcard or search The whole course of treatment for for MHRA Yellow Card in the Google vaginal thrush or penile thrush is one capsule which you take by mouth. Take Play or Apple App Store. By reporting side effects you can help the capsule with a glass of water. provide more information on the safety Some women and men notice an of this medicine. improvement after one day and the 5.

Possible side effects

not listed in this leaflet, (inflammation of the end of the penis). please tell your doctor or pharmacist. It causes any of the following symptoms: Common: may affect up to 1 in 10 soreness and redness of the penis, people tightness of the foreskin and a white,

• headache odourless discharge from the penis.
• stomach discomfort, diarrhoea, How to avoid future recurrences feeling sick, vomiting
• Wear cotton underwear and avoid
• increase in blood tests of liver tight clothing function
• Wash daily
• rash.
• After going to the toilet, wipe Uncommon: may affect up to 1 in 100 yourself from front to back as a people thrush infection may be transferred
• anaemia, reduction in red blood from the bowel cells which can make skin pale and • Change your sanitary protection cause weakness or breathlessness regularly
• decreased appetite
• Try to avoid washing with perfumed
• inability to sleep, feeling drowsy soaps and using vaginal deodorants
• fits, dizziness, sensation of spinning,
• Do not wash or rub yourself hard tingling, prickling or numbness, with sponges or flannels changes in sense of taste
• constipation, difficulty in digestion, If you are still worried or have any questions about the symptoms or the wind, dry mouth treatment of thrush, contact your doctor
• muscle pain or pharmacist for advice.
• low blood potassium, which may cause muscle cramps or weakness, Marketing Authorisation Holder and nausea and changes in heart Manufacturer: rhythm Relonchem Limited,
• increased sweating Cheshire House, Gorsey Lane, Widnes,
• tiredness, general feeling of being Cheshire, WA8 0RP, UK. unwell, fever. Distributor: The Boots Company PLC. Rare: may affect up to 1 in 1,000 people Nottingham NG2 3AA
• lower than normal white blood cells Product Licence Number: (you may have more infections than PL 20395/0042 usual such as sore throats, fever or flu-like symptoms)
• lower than normal blood cells that help to stop bleeding (you may This leaflet was last revised in have unexplained bruising or November 2025. bleeding) D24-0473 Version C
• red or purple discoloration of the PON/DRUGS/08 13 2289 skin which may be caused by low contact your doctor before taking this medicinal product. Information on sodium content Boots Thrush Treatment 150 mg Capsule contain less than 1 mmol sodium (23 mg) per capsule, that is to say essentially 'sodium-free'.

platelet count, other blood cell changes

• blood chemistry changes (high blood levels of cholesterol, fats)
• shaking

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How to store it

Boots Thrush thrush should clear up after 2 days. If Treatment 150 mg Capsule symptoms persist for more than 7 days, consult your doctor. Keep this medicine out of the sight and reach of children. If after treatment with Boots Thrush Treatment 150 mg Capsule you have a Do not use this medicine after the expiry reoccurrence of thrush, you should only date which is stated on the carton. The take this product again if it has been expiry date refers to the last day of that month. more than 7 days since your last The product does not require any treatment. If you experience a thrush infection special storage conditions within more than twice over a six month Europe. period, consult your doctor. Do not throw away any medicines via Remember that Fluconazole can only wastewater or household waste. Ask treat thrush. It cannot treat other your pharmacist how to throw away infections of the genitals. medicines you no longer use. If you still have any sort of symptoms These measures will help protect the one or two days after you have taken environment. Fluconazole, you should visit your doctor in case you have another type of 6. Contents of the pack and other information infection. What Boots Thrush Treatment 150 mg If you take more Boots Thrush Capsule contains Treatment 150 mg Capsule than you

• The active substance is should Fluconazole. If you (or someone else) swallow a lot Each capsule contains 150 mg of of capsules at the same time, or you Fluconazole. think a child has swallowed any of the
• The other ingredients are lactose capsules, contact your doctor, monohydrate, maize starch, sodium pharmacist or hospital emergency department immediately. lauryl sulphate, colloidal silicon dioxide and magnesium stearate. 4. Possible side effects The capsule shell is gelatin and the Like all medicines, this medicine can colouring agents are titanium cause side effects, although not dioxide (E171) and Patent Blue V everybody gets them. These can be (E131). seen even with a single dose of What Boots Thrush Treatment 150 mg 150 mg. Capsule looks like and the contents of STOP taking Boots Thrush Treatment the pack 150 mg Capsule straight away and contact your doctor immediately if you Each capsule has a blue body and cap. Boots Thrush Treatment 150 mg Capsule experience: come in a pack containing one capsule.
• a serious allergic reaction Further information about thrush (anaphylaxis) or hypersensitivity Vaginal thrush (candidiasis) is a including an itchy rash (hives), common infection that most women itching, sore mouth or eyes, fever, suffer from at some stage in their lives swelling of the face, lips, throat or tongue and is not caused by lack of personal
• a sudden wheeziness or tightness of hygiene. the chest Thrush is caused by a yeast (fungus)
• liver problems such as yellowing of called Candida, which lives harmlessly the skin or whites of the eyes in the vagina and other parts of the (jaundice), dark coloured urine, or body without ever being noticed. changes in the way your liver works However, the natural balance that (that may show up in blood tests) keeps Candida under control can be
• a severe skin rash with flushing, upset by many factors such as hormonal fever, blisters or ulcers changes (menstruation, contraceptive (Stevens-Johnson syndrome) pill, pregnancy, menopause), poor
• a severe rash with reddening, health, antibiotics, perfumed soaps, peeling and swelling of the skin that bath additives and tight clothing. looks like a burn (toxic epidermal If the natural pH balance is altered, the necrolysis) level of yeast increases and can
• hypersensitivity reaction with skin develop into a thrush infection causing rash, fever, swollen glands, any of the following symptoms: increase in a type of white blood cell (eosinophilia) and inflammation persistent burning and/or itching around the vagina and vulva, redness, of internal organs (liver, lungs, swelling and soreness of the tissues of heart, kidneys and large intestine) the vagina and the vulva and a whitish,
• Widespread rash, high body temperature and enlarged lymph odourless discharge from the vagina. node (DRESS syndrome or drug Not everybody who has thrush has all hypersensitivity syndrome). these symptoms; you may have only one of them. Other side effects: Additionally, if any of the following side In men, Candida can also cause thrush effects gets serious, or if you notice any – a condition called balanitis

Contents of the pack and other information

1. What Boots Thrush Treatment 150 mg Capsule is and what it is used for Boots Thrush Treatment 150 mg Capsule is a full course of treatment for thrush. Only use this product if you have been previously diagnosed by your doctor as having thrush. The active substance is Fluconazole. It belongs to a group of medicines called azoles and is an antifungal agent. It fights the cause of infections such as penile thrush as well as vaginal thrush.