Pharmacy Guide

Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.

Pharmacy Guide

Patient leaflets and SmPCs, drug interaction checker, official dosages and NHS pharmacy opening hours — all in one place.

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Boots Sleepeaze 25mg Tablets

⚠ This medicine appears to have been discontinued

The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.

If you were prescribed this medicine, other products containing Diphenhydramine hydrochloride may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.

Active substance: Diphenhydramine hydrochloride

Equivalent medicines (same active substance, strength and form)

Source: electronic medicines compendium (emc)
Official leaflet: Read the PIL on emc

What you need to know before you take it

e Sleepeaze 25 mg Tablets

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Not to be used by children under 16 years. Not to be used by the elderly with confusion.

  • Do not take more than the recommended dose.
  • Do not take extra tablets if you wake up in the night.
  • Do not take for more than 2 weeks without consulting a doctor.

Sleepeaze 25 mg Tablets with food, drink and alcohol

Do not take this medicine for more than 2 weeks without consulting your doctor.

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The recommended dose for adults and children aged 16 years and over: Swallow 2 tablets with water 20 minutes before you go to bed.

Talk to your doctor or pharmacist before taking these tablets if you are taking any prescribed medicines; particularly tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs prescribed for depression) within the last two weeks, atropine (used to dilate pupils of the eyes) or medicines which make you drowsy. Do not take Sleepeaze 25mg Tablets together with medicines that can produce a change in heart rhythm called QT prolongation which is seen by electrocardiogram (ECG). If you are not sure, please consult your doctor before taking this medicine. Avoid the use of other antihistamines including those used on your skin and in cold and cough medicines, while taking this medicine.

How to take it

Sleepeaze 25 mg Tablets

Warnings and precautions

G3U60QAJB5 L164

PL 02855/0071

139.7 x 228.6mm

Pantone

Technical

N/A

273 c

Cutter

N/A

N/A

Guides

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

  • Confusion, excitation e.g. increased energy, restlessness, nervousness (the elderly are more likely to experience these effects)
  • Difficulty urinating or inability to pass urine
  • Thicker bronchial mucus
  • Blurred vision
  • Feeling or being sick, stomach problems
  • Muscle twitching
  • Reduced sense of touch
  • An irresistible urge to move your legs and other limbs (restless leg syndrome)

Reporting of side effects:

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in Google Play or Apple App store. By reporting side effects you can help provide more information on the safety of this medicine.

Possible side effects

Driving and using machines

Boots Sleepeaze 25mg Tablets

Version Information

Do not take a double dose to make up for a forgotten dose. Take the next dose at the usual time as described in this leaflet. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Talk to your doctor before taking this medicine if you are pregnant, trying to become pregnant, or breast-feeding.

  • if you have ever had an allergic reaction to diphenhydramine hydrochloride or any of the other ingredients (listed in Section 6)
  • if you have an obstruction in your stomach or gut (for example, because of an ulcer).

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If you forget to take Sleepeaze 25 mg Tablets

Pregnancy, breast-feeding and fertility

Do not take this medicine:

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If you take more Sleepeaze 25 mg Tablets than you should

Do not drink alcohol while using this medicine.

How to store it

Sleepeaze 25 mg Tablets Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date (EXP) stated on the pack. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment. Store below 25 oC.

Contents of the pack and other information

What Sleepeaze 25 mg Tablets contain

  • The active substance: Each tablet contains Diphenhydramine Hydrochloride 25 mg.
  • The other ingredients are: Anhydrous lactose, microcrystalline cellulose, maize starch, stearic acid and silicon dioxide. What Sleepeaze 25 mg Tablets look like and contents of the pack Packs of Sleepeaze 25 mg Tablets contain 4, 8, 16, 20 or 24 tablets. Not all pack sizes may be marketed. Marketing authorisation holder is Omega Pharma Ltd., Wrafton, Braunton, Devon, EX33 2DL, United Kingdom and all enquiries should be sent to this address. Manufacturer Wrafton Laboratories Ltd, Wrafton, Braunton, North Devon, EX33 2DL, U.K. This leaflet was last revised in January 2025.

G3U60QAJB5

Frequently asked questions about Boots Sleepeaze 25mg Tablets

How do I take Boots Sleepeaze 25mg Tablets?

Boots Sleepeaze 25mg Tablets comes as tablet containing 25mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.

What is the active substance in Boots Sleepeaze 25mg Tablets?

The active substance in Boots Sleepeaze 25mg Tablets is diphenhydramine hydrochloride.

Are there equivalent medicines to Boots Sleepeaze 25mg Tablets?

Medicines with the same active substance, strength and form include: Diphenhydramine Hydrochloride 25 mg Tablets. They are interchangeable only if your prescriber or pharmacist says so.

Where does this information come from?

This leaflet reproduces the patient information leaflet approved for Boots Sleepeaze 25mg Tablets, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.

Can I get Boots Sleepeaze 25mg Tablets without a prescription?

Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.

About this leaflet

The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.

Medical disclaimer: This page is for information only and does not replace advice from your doctor or pharmacist. Always read the leaflet supplied with your medicine. If you are unwell, call NHS 111; in an emergency, call 999.

Medicines with the same active substance: Diphenhydramine hydrochloride (17 medicines)
See every medicine containing this substance, or browse the full A–Z of active substances.

💬 Ask about this leaflet

Ask anything about Boots Sleepeaze 25mg Tablets. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.

Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.

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