The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.Source: electronic medicines compendium (emc), DatapharmActive substance: fexofenadine hydrochlorideOfficial document: view the original leaflet on emc →Medical disclaimer: This page is for information only and does not replace advice from your doctor or pharmacist. Always read the leaflet supplied with your medicine. If you are unwell, call NHS 111; in an emergency, call 999.

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Allevia Hives 180 mg tablets

⚠ This medicine appears to have been discontinued

The electronic medicines compendium (emc) no longer publishes a Summary of Product Characteristics for this product, which usually means it is no longer marketed in the UK. The patient leaflet below is kept for reference, but the product may not be available.

If you were prescribed this medicine, other products containing Fexofenadine hydrochloride may still be available. Do not stop your treatment — ask your pharmacist or GP what to use instead.

Active substance: Fexofenadine hydrochloride

Equivalent medicines (same active substance, strength and form)

→ Almerg 180 mg Film-Coated Tablets brand

→ Histahive 180 mg Film-coated Tablets brand

→ Telfast 180mg Film-coated Tablets brand

→ Fexofenadine 180mg film coated tablets

→ Fexofenadine Cipla 180 mg film-coated tablets

and 2 more with the same active substance, strength and form

Source: electronic medicines compendium (emc)

Official leaflet: Read the PIL on emc

What it is and what it is used for

for 2. What you need to know before you take Allevia Hives 180mg 3. How to take Allevia Hives 180mg 4. Possible side effects 5. How to store Allevia Hives 180mg 6. Contents of the pack and other information

If any of these apply to you, or if you are not sure, tell your doctor or pharmacist before taking Allevia Hives 180mg. Other medicines and Allevia Hives 180mg Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is especially important for the following medicines: y Erythromycin (an antibiotic) y Ketoconazole (a treatment for fungal infections) If you are taking apalutamide (a medicine to treat prostate cancer), as the effect of fexofenadine may be decreased. Indigestion remedies containing aluminium and magnesium may affect the action of Allevia Hives 180mg by lowering the amount of medicinal product absorbed. It is recommended that you leave about 2 hours between the time that you take Allevia Hives 180mg and your indigestion remedy. Allevia Hives 180mg with food and drink Allevia Hives 180mg should be taken before meals with water. Pregnancy and breast-feeding If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Allevia Hives 180mg should not be taken during pregnancy and whilst breast-feeding unless advised by a doctor.

1. What Allevia Hives 180mg is and what it is used for Allevia Hives 180mg contains fexofenadine hydrochloride, which is a non-drowsy antihistamine. Allevia Hives 180mg is used in adults and adolescents of 12 years and older to relieve the symptoms that occur with allergic skin reactions (chronic idiopathic urticaria) such as red, raised, itchy skin, which is often known as hives or nettle rash. Allevia Hives 180mg is not suitable for children under 12 years of age. You must talk to a doctor if you do not feel better or if you feel worse after taking this medicine.

Driving and using machines Allevia Hives 180mg is unlikely to affect your ability to drive or operate machinery. However, you should check that these tablets do not make you feel sleepy or dizzy before driving or operating machinery. Allevia Hives 180mg contains sodium This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially 'sodium-free'.

2. What you need to know before you take Allevia Hives 180mg

How to take it

Allevia Hives 180mg

Do not take Allevia Hives 180mg y if you are allergic to fexofenadine or any of the other ingredients of this medicine (listed in section 6). Warnings and precautions Talk to your doctor or pharmacist before taking Allevia Hives 180mg if you: y have problems with your liver or kidneys y are elderly y have or ever had heart problems, as fexofenadine, like other antihistamines may cause your heart to beat faster (tachycardia) or you feel your heart beating (palpitations).

Code sécurité R400639

Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. For adults and adolescents aged 12 years and over The recommended dose is one tablet (180 mg) daily. Take the tablet with water before a meal. This medicine starts to relieve your symptoms within 1 hour and lasts for 24 hours. If the symptoms of allergic skin reactions persist, or gets worse or other symptoms appear, you should stop the treatment and consult a doctor. Do not exceed the stated dose. Do not give to children below 12 years of age.

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R400639

Version N° créé le par modifié le par

02/04/2026 DERIGNY C 11/06/2026 DERIGNY C

Type Article

Notice simple

Nom du produit Référence article Dosage Quantité

Allevia Hives R400639 180 mg cprs

Laboratoires Opella. Pays Grande-Bretagne

Couleur Nbre/Réf.

N° version Logo/Name N° version Country Ex. N° plan Dimensionnel N° plan positionnement Dimensions Taille mini caractères

N.A. N.A. 1-606092 COM-P606092-1c 150 x 210 mm 9 pts

Code sécurité R400639 Numéro de pages 2/2

NOIR

If you take more Allevia Hives 180mg than you should If you have accidentally taken more than this leaflet recommended, contact the nearest hospital emergency department or tell your doctor or pharmacist immediately. Remember to take the pack and any remaining tablets with you. The most common signs of overdose are dizziness, drowsiness, fatigue and dry mouth. If you forget to take Allevia Hives 180mg Do not take a double dose to make up for a forgotten tablet. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. If you get any of the following symptoms after taking these tablets you should contact your doctor or pharmacist immediately as these may be signs of a serious allergic reaction: y swelling of the face, lips, tongue or throat and difficulty breathing The following undesirable effects have been reported in clinical trials, with an incidence similar to those observed in patient who did not receive the drug (placebo). Common side effects (may affect up to 1 in 10 people): y headache y drowsiness y feeling sick (nausea) y dizziness. Uncommon side effects (may affect up to 1 in 100 people): y tiredness y sleepiness. Additional side effects (frequency not known: cannot be estimated from the available data) which may occur are: y difficulty sleeping (insomnia) y sleeping disorders y bad dreams y nervousness y fast or irregular heart beat y feel your heart beating (palpitations) y diarrhoea y skin rash and itching y hives y serious allergic reactions which can cause swelling of the face, lips, tongue or throat, flushing, chest tightness, and difficulty breathing y blurred vision. Reporting of side effects If you get any side effects, talk to your doctor, or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

How to store it

Allevia Hives 180mg Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the blister and carton after EXP. The expiry date refers to the last day of that month. This medicine does not require any special storage condition. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Contents of the pack and other information

What Allevia Hives 180mg contains y The active substance is fexofenadine hydrochloride. Each tablet contains 180 mg of fexofenadine hydrochloride. y The other ingredients are: □ Tablet core: microcrystalline cellulose, pregelatinised maize starch, croscarmellose sodium, magnesium stearate. □ Film coating: hypromellose, povidone, titanium dioxide (E171), colloidal anhydrous silica, macrogol 400 and iron oxide (E172). What Allevia Hives 180mg looks like and contents of the pack Allevia Hives 180mg film-coated tablets are peach coloured, capsule shaped tablets marked with "018" on one side and a scripted "e" on the other. Allevia Hives 180mg is presented in blister packs of 2 (sample pack), 10,15, 20 and 30 tablets. Not all pack sizes are marketed. Marketing Authorisation Holder and Manufacturer Marketing Authorisation Holder: Opella, 410 Thames Valley Park Drive Reading, Berkshire, RG6 1PT, UK Manufacturer: Opella Healthcare International SAS 56, route de Choisy 60200 Compiègne France This leaflet was last revised in June 2026.

For electronic version of this leaflet scan the QR code. This paper leaflet might not be the latest version and thus different to the electronic leaflet which is the last updated version available.

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Frequently asked questions about Allevia Hives 180 mg tablets

How do I take Allevia Hives 180 mg tablets?

Allevia Hives 180 mg tablets comes as tablet containing 180mg. Always follow the dose your doctor or pharmacist has given you, and read the leaflet that comes with the medicine.

What is the active substance in Allevia Hives 180 mg tablets?

The active substance in Allevia Hives 180 mg tablets is fexofenadine hydrochloride.

Are there equivalent medicines to Allevia Hives 180 mg tablets?

Medicines with the same active substance, strength and form include: Almerg 180 mg Film-Coated Tablets, Histahive 180 mg Film-coated Tablets, Telfast 180mg Film-coated Tablets. In total there are 7 equivalent products. They are interchangeable only if your prescriber or pharmacist says so.

Where does this information come from?

This leaflet reproduces the patient information leaflet approved for Allevia Hives 180 mg tablets, as published on the electronic medicines compendium (emc). The version printed inside your medicine’s packaging is the one that applies to you.

Can I get Allevia Hives 180 mg tablets without a prescription?

Whether a medicine is available over the counter or on prescription only depends on its licence. Check the leaflet, or ask your pharmacist — they can tell you straight away.

About this leaflet

The text above reproduces the patient information leaflet approved for this medicine, restructured for easier reading.

Source: electronic medicines compendium (emc), Datapharm
Active substance: fexofenadine hydrochloride
Official document: view the original leaflet on emc →

Medical disclaimer: This page is for information only and does not replace advice from your doctor or pharmacist. Always read the leaflet supplied with your medicine. If you are unwell, call NHS 111; in an emergency, call 999.

Medicines with the same active substance: Fexofenadine hydrochloride (18 medicines)

See every medicine containing this substance, or browse the full A–Z of active substances.

⚕For healthcare professionals — Summary of Product Characteristics (SmPC)Full SmPC: dosage, interactions, contraindications, warnings+

Technical information intended for healthcare professionals (doctors and pharmacists). The Summary of Product Characteristics (SmPC) is the official document approved by the MHRA/EMA. It does not replace the patient leaflet or a doctor’s advice.

4.1. Therapeutic indications

Allevia Hives 180 mg is indicated in adults and children 12 years and older for the relief of symptoms associated with chronic idiopathic urticaria.

4.2. Posology and method of administration

Posology

Adults

The recommended dose of fexofenadine hydrochloride for adults is 180 mg once daily taken before a meal.

Fexofenadine is a pharmacologically active metabolite of terfenadine.

Paediatric population

• Adolescents aged 12 years and over

The recommended dose of fexofenadine hydrochloride for adolescents aged 12 years and over is 180 mg once daily taken before a meal.

• Children under 12 years of age

The efficacy and safety of fexofenadine hydrochloride 180 mg has not been studied in children under 12.

Special populations

Studies in special risk groups (elderly, renally or hepatically impaired patients) indicate that it is not necessary to adjust the dose of fexofenadine hydrochloride in these patients.

Method of administration

Allevia Hives 180 mg tablet is for oral use

4.3. Contraindications

Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.

4.4. Special warnings and precautions for use

As with most new medicinal products there is only limited data in the elderly and renally or hepatically impaired patients.

Fexofenadine hydrochloride should only be administered in these special groups on the advice of a doctor.

Patients with a history of or ongoing cardiovascular disease should be warned that, antihistamines as a medicine class, have been associated with the adverse reactions tachycardia and palpitations (see section 4.8) and should use fexofenadine hydrochloride only on the advice of their doctor.

Excipient

This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially 'sodium-free.'

4.5. Interaction with other medicinal products and other forms of interaction

Fexofenadine does not undergo hepatic biotransformation and therefore will not interact with other medicinal products through hepatic mechanisms. Fexofenadine is a P-glycoprotein (P-gp) and organic-anion-transporting polypeptide (OATP) substrate. Concomitant use of fexofenadine with P-gp inhibitors or inducers can affect the exposure to fexofenadine. Coadministration of fexofenadine hydrochloride with P-gp inhibitors, erythromycin or ketoconazole has been found to result in a 2-3 times increase in the level of fexofenadine in plasma. The changes were not accompanied by any effects on the QT interval and were not associated with any increase in adverse reactions compared to the medicinal products given singly.

A clinical drug-drug interaction study showed that co-administration of apalutamide (a weak inducer of P-gp) and a single oral dose of 30 mg fexofenadine resulted in a 30 % decrease in AUC of fexofenadine.

No interaction between fexofenadine and omeprazole was observed. However, the administration of an antacid containing aluminium and magnesium hydroxide gels 15 minutes prior to fexofenadine hydrochloride caused a reduction in bioavailability, most likely due to binding in the gastrointestinal tract. It is advisable to leave 2 hours between administration of fexofenadine hydrochloride and aluminium and magnesium hydroxide containing antacids.

4.6. Fertility pregnancy and lactation

Pregnancy

There are no adequate data from the use of fexofenadine hydrochloride in pregnant women. Limited animal studies do not indicate direct or indirect harmful effects with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3). Fexofenadine hydrochloride should not be used during pregnancy unless on the advice of a doctor.

Breast-feeding

There are no data on the content of human milk after administering fexofenadine hydrochloride. However, when terfenadine was administered to nursing mothers fexofenadine was found to cross into human breast milk. Therefore fexofenadine hydrochloride is not recommended for mothers breast-feeding their babies. Breast-feeding women should only use fexofenadine hydrochloride if advised to do so by a doctor.

Fertility

No human data on the effect of fexofenadine hydrochloride on fertility are available. In mice, there was no effect on fertility with fexofenadine hydrochloride treatment (see section 5.3).

4.7. Effects on ability to drive and use machines

On the basis of the pharmacodynamic profile and reported adverse reactions it is unlikely that fexofenadine hydrochloride tablets will produce an effect on the ability to drive or use machines. In objective tests, fexofenadine has been shown to have no significant effects on central nervous system function. This means that patients may drive or perform tasks that require concentration. However, in order to identify sensitive people who have an unusual reaction to medicinal products, it is advisable to check the individual response before driving or performing complicated tasks.

4.8. Undesirable effects

The following frequency rating has been used, when applicable:

Very common ≥1/10;

Common ≥1/100 and <1/10;

Uncommon ≥1/1,000 and <1/100;

Rare ≥1/10,000 and <1/1,000;

Very rare <1/10,000

Not known (frequency cannot be estimated from the available data).

Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.

In adults, the following undesirable effects have been reported in clinical trials, with an incidence similar to that observed with placebo:

Nervous system disorders

Common: headache, drowsiness, dizziness

Gastrointestinal disorders

Common: nausea

General disorders and administration site conditions

Uncommon: fatigue

In adults, the following undesirable effects have been reported in post-marketing surveillance. The frequency with which they occur is not known (can not be estimated from available data):

Immune system disorders

hypersensitivity reactions with manifestations such as angioedema, chest tightness, dyspnoea, flushing and systemic anaphylaxis

Psychiatric disorders

insomnia, nervousness, sleep disorders or nightmares/excessive dreaming (paroniria)

Cardiac disorders

tachycardia, palpitations

Gastrointestinal disorders

diarrhoea

Skin and subcutaneous tissue disorders

rash, urticaria, pruritus

Eye disorders

Vision blurred.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

4.9. Overdose

Dizziness, drowsiness, fatigue and dry mouth have been reported with overdose of fexofenadine hydrochloride. Single doses up to 800 mg and doses up to 690 mg twice daily for 1 month or 240 mg once daily for 1 year have been administered to healthy subjects without the development of clinically significant adverse reactions as compared with placebo. The maximum tolerated dose of fexofenadine hydrochloride has not been established.

Standard measures should be considered to remove any unabsorbed medicinal product. Symptomatic and supportive treatment is recommended. Haemodialysis does not effectively remove fexofenadine hydrochloride from blood.

💬 Ask about this leaflet

Ask anything about Allevia Hives 180 mg tablets. The assistant answers only from this leaflet — if the leaflet does not cover it, it will say so. It does not give medical advice.

Answers come from the patient leaflet published on the electronic medicines compendium (emc). They are not medical advice. Ask a pharmacist or your GP if you are unsure. For urgent help call NHS 111, or 999 in an emergency.

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